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Date of Award

1971

Document Type

Dissertation

Degree Name

Doctor of Philosophy (Ph.D.)

First Advisor

Donald Barker

Second Advisor

Ivan W. Rowland

First Committee Member

Carl C. Riedesel

Second Committee Member

John K. Brown

Third Committee Member

James C. King

Abstract

It would seem appropriate that studies be conducted on the development of an oral inhalation dosage form antinauseant. The present project will consist of developing and testing a series of aerosol formulations to determine their feasibility in antinauseant therapy. In vitro pressure, valve release, spray pattern, particle size, and aging studies will be performed. The present work will also include an in vivo evaluation of promising formulations.

Pages

67

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