Comparison of expression of the GDNF family neurotrophic factors in dental pulp stem cells with deciduous and adult teeth

Authors

Kamille Mercado, University of the Pacific
Nan (Tori) Xiao, University of the PacificFollow

Department

Biomedical Sciences

Document Type

Article

Publication Title

Journal of the California Dental Association

ISSN

1043-2256

Volume

12

Issue

45

First Page

667

Last Page

669

Publication Date

12-2017

Abstract

The glial cell line-derived neurotrophic factor (GDNF) family has a role in neuron growth within the peripheral and central nervous systems. This makes it a potential therapeutic agent for neurological conditions like Parkinson’s disease and epilepsy. GDNF has also been implicated in murine odontogenesis. In permanent and deciduous human dental pulp stem cells, this study found that GDNF family members and receptors are expressed, indicating neurotrophic factors may play a role in dental pulp regeneration.

Comments

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Recommended Citation

Mercado, K., & Xiao, N. (2017). Comparison of expression of the GDNF family neurotrophic factors in dental pulp stem cells with deciduous and adult teeth. Journal of the California Dental Association, 12(45), 667–669.
https://scholarlycommons.pacific.edu/dugoni-facarticles/416