Title

The oral microbiota: living with a permanent guest

ORCiD

David M. Ojcius: 0000-0003-1461-4495

Document Type

Article

Publication Title

DNA and Cell Biology

ISSN

1044-5498

Volume

28

Issue

8

DOI

10.1089/dna.2009.0874

First Page

405

Last Page

411

Publication Date

8-1-2009

Abstract

The oral cavity of healthy individuals contains hundreds of different bacterial, viral, and fungal species. Many of these can associate to form biofilms, which are resistant to mechanical stress or antibiotic treatment. Most are also commensal species, but they can become pathogenic in responses to changes in the environment or other triggers in the oral cavity, including the quality of an individual's personal hygiene. The complexity of the oral microbiome is being characterized through the newly developed tools of metagenomics. How the microbiome of the oral cavity contributes to health and disease is attracting the interest of a growing number of cell biologists, microbiologists, and immunologists.