Title

Development of optimized synthetic route towards dicyclohexano-18-crown-6

Poster Number

16C

Lead Author Major

Biochemistry

Lead Author Status

Senior

Format

Poster Presentation

Faculty Mentor Name

Vyacheslav Samoshin

Faculty Mentor Email

vsamoshin@pacific.edu

Faculty Mentor Department

Chemistry

Graduate Student Mentor Name

Carim van Beek

Graduate Student Mentor Email

c_vanbeek@u.pacific.edu

Graduate Student Mentor Department

Pharmaceutical and Chemical Sciences

Abstract/Artist Statement

Crown ethers are large cyclic molecules notable for the ability to selectively bind a variety of metal ions and for their application in phase transfer catalysis. To this extent, we have explored an alternative synthetic route towards dicyclohexano-18-crown-6, a very important crown ether. The ultimate goal is to optimize the yield for this synthesis. In the future, we aim to use this optimized route in the synthesis of crown ethers with additional functional groups, a novel concept.

Crown ethers are currently characterized by their difficulty in removal from solution. Equipping crown ethers with additional functional groups would allow attachment of these molecules to an easily removable solid support, eliminating this drawback.

Location

DeRosa University Center, Ballroom

Start Date

28-4-2018 10:00 AM

End Date

28-4-2018 12:00 PM

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Apr 28th, 10:00 AM Apr 28th, 12:00 PM

Development of optimized synthetic route towards dicyclohexano-18-crown-6

DeRosa University Center, Ballroom

Crown ethers are large cyclic molecules notable for the ability to selectively bind a variety of metal ions and for their application in phase transfer catalysis. To this extent, we have explored an alternative synthetic route towards dicyclohexano-18-crown-6, a very important crown ether. The ultimate goal is to optimize the yield for this synthesis. In the future, we aim to use this optimized route in the synthesis of crown ethers with additional functional groups, a novel concept.

Crown ethers are currently characterized by their difficulty in removal from solution. Equipping crown ethers with additional functional groups would allow attachment of these molecules to an easily removable solid support, eliminating this drawback.