Preview

image preview
HbBcd.svg (7 kB)

Creation Date

2019

Description

The Bicoid (Bcd) gradient is shallow, Bicoid concentration (y-axis) degrades over about 1/2 of total embryo length (x-axis). However, this shallow gradient provides positional information for Hunchback (Hb), which is translated as long as there are even low levels of Bicoid protein1,2. This sharp Hunchback gradient neatly splits the embryo into anterior and posterior halves. Later in development the presence of high Hb + high Bcd, high Hb, low Bcd, and low Hb + low Bcd will be read by different transcription factors to produce broad stripes in the embryo

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.

Keywords

bicoid, hunchback, drosophila, evodevo, evolutionary developmental biology, gradient, model

Share

COinS