Title

Comparison of the effect of cigarette smoke on mesenchymal stem cells and dental stem cells

ORCiD

David M. Ojcius: 0000-0003-1461-4495

Document Type

Article

Publication Title

American Journal of Physiology - Cell Physiology

ISSN

0363-6143

Volume

320

Issue

2

DOI

10.1152/ajpcell.00217.2020

First Page

C175

Last Page

C181

Publication Date

2-1-2021

Abstract

The persistent prevalence of cigarette smoking continues to contribute to preventable disease and death in the United States. Although much is known about the deleterious systemic effects of cigarette smoke and nicotine, some clinically relevant areas, such as the impact of cigarette smoke and nicotine on stem cells and the subsequent implications in regenerative medicine, still remain unclear. This review focuses on recent studies on the effect of cigarette smoke and one of its deleterious components, nicotine, on mesenchymal stem cells, with an emphasis on dental stem cells.

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