Antimicrobial effects of frankincense extracts on oral pathogens, David Vang, Homer Asadi, Harmony Matshik Dakafay, German Moncada, David Ojcius, Cassio Almeida-da-Silva
Cassio Silva

Antimicrobial effects of frankincense extracts on oral pathogens, David Vang, Homer Asadi, Harmony Matshik Dakafay, German Moncada, David Ojcius, Cassio Almeida-da-Silva
Cassio Silva

Prevalence of Dog Heartworm (Dirofilaria immitis) infection in invasive Aedes aegypti and Aedes albopictus mosquitoes in Southern California, Irene Hui Ying Lee, Donghwi Kim, Romina Lee
Pacific Undergraduate Research and Creativity Conference (PURCC)

Antimicrobial effects of frankincense extracts on oral pathogens, David Vang, Homer Asadi, Harmony Matshik Dakafay, German Moncada, David Ojcius, Cassio Almeida-da-Silva
Pacific Research & Scholarship Day

What is the prevalence of Dirofilaria immitis (dog heartworm) in invasive Aedes mosquitoes?, Leen Yousef, Johan Espinoza Corrales, Daniela H. Dolar, Taylor K. Trieu, Aisha Popalzai, Agamchat Dhami
Pacific Undergraduate Research and Creativity Conference (PURCC)

A dual role for P2X7 receptor during Porphyromonas gingivalis infection, E. S. Ramos-Junior, Ana Carolina Morandini, Cassio Almeida-da-Silva, E. J. Franco, J. Potempa, K. A. Nguyen, A. C. Oliveira, D. S. Zamboni, David M. Ojcius, J. Scharfstein, Robson Coutinho-Silva
Cassio Silva

Announcing the "Pacific Journal of Health", David M. Ojcius, Michele Gibney
David M. Ojcius

Chlamydia pneumoniae is present in the dental plaque of periodontitis patients and stimulates an inflammatory response in gingival epithelial cells, Cassio Silva, Tamer Alpagot, Ye Zhu, Sierra Sonho Lee, Brian P. Roberts, Shu-Chen Hung, Norina Tang, David Ojcius
David M. Ojcius

Announcing the "Pacific Journal of Health", David M. Ojcius, Michele Gibney
Michele Gibney

Systemic Immunologic Consequences of Chronic Periodontitis., D K. Gaudilliere, A Culos, K Djebali, A S. Tsai, E A. Ganio, W M. Choi, X Han, A Maghaireh, B Choisy, Q Baca, J F. Einhaus, J J. Hedou, B Bertrand, K Ando, R Fallahzadeh, M S. Ghaemi, R Okada, N Stanley, A Tanada, M Tingle, T Alpagot, J A. Helms, M S. Angst, N Aghaeepour, B Gaudilliere
Xiaoyuan Han

Announcing the "Pacific Journal of Health", David M. Ojcius, Michele Gibney
Pacific Research & Scholarship Day

Chlamydia pneumoniae is present in the dental plaque of periodontitis patients and stimulates an inflammatory response in gingival epithelial cells, Cassio Almeida-da-Silva, Tamer Alpagot, Ye Zhu, Sierra Sonho Lee, Brian P. Roberts, Shu-Chen Hung, Norina Tang, David Ojcius
Pacific Research & Scholarship Day

Role of Anti Angiogenic Therapy in Prevention of Recurrence in Hormonal Positive Breast Cancer: A Secondary Prevention Strategy and Method of Therapy, M. A. Nezami, Jessica Garner
Jessica Garner

Pinicolol B from Antrodia cinnamomea induces apoptosis of nasopharyngeal carcinoma cells, Tsung-Ru Wu, Tsung-Teng Huang, Jan Martel, Jian-Ching Liau, Chen-Yaw Chiu, Yann-Lii Leu, Wei-Ting Jian, I-Te Chang, Chia-Chen Lu, David M. Ojcius, Yun-Fei Ko, Hsin-Chih Lai, John Ding-E. Young
All Dugoni School of Dentistry Faculty Articles

Creation of an immunodeficient HLA-transgenic mouse (HUMAMICE) and functional validation of human immunity after transfer of HLA-matched human cells, Yang Zeng, Bingrun Liu, Marie-Therese Rubio, Xinyue Wang, David M. Ojcius, Ruoping Tang, Antoine Durrbach, Zhitao Ru, Yusen Zhou, Yu-Chun Lone
All Dugoni School of Dentistry Faculty Articles

A dual role for P2X7 receptor during Porphyromonas gingivalis infection, E. S. Ramos-Junior, Ana Carolina Morandini, C. L. Almeida-da-Silva, E. J. Franco, J. Potempa, K. A. Nguyen, A. C. Oliveira, D. S. Zamboni, David M. Ojcius, J. Scharfstein, Robson Coutinho-Silva
David M. Ojcius

A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells, Kuo-Feng Weng, Chuan-Tien Hung, Po-Ting Hsieh, Mei-Ling L. Li, Guang-Wu Chen, Yu-An Kung, Peng-Nien Huang, Rei-Lin Kuo, Li-Lien Chen, Jing-Yi Lin, Robert Yung-Liang Wang, Shu-Jen Chen, Petrus Tang, Jim-Tong Horng, Hsing-I Huang, Jen-Ren Wang, David M. Ojcius, Gary Brewer, Shin-Ru Shih
David M. Ojcius

ATP activates a Reactive Oxygen Species-dependent oxidative stress response and secretion of pro-inflammatory cytokines in macrophages, Christiane M. Cruz, Alessandra Rinna, Henry Jay Forman, Ana L. M. Ventura, Pedro M. Persechini, David M. Ojcius
David M. Ojcius

A role for mitogen-activated protein kinase (Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death, Rodolphe Auger, Iris Motta, Karim Benihoud, David M. Ojcius, Jean M. Kanellopoulos
David M. Ojcius

Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin, Tsung-Teng Huang, Fu-Guo Liu, Chia-Fong Wei, Chia-Chen Lu, Chang-Chieh Chen, Hung-Chi Lin, David M. Ojcius, Hsin-Chih Lai
David M. Ojcius

Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas gingivalis, Özlem Yilmaz, Thomas Jungas, Philippe Verbeke, David M. Ojcius
David M. Ojcius

Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages leading to the release of pro-inflammatory cytokines, Bruce J. Shenker, David M. Ojcius, Lisa P. Walker, Ali Zekavat, Monika Damek Scuron, Kathleen Boesze-Battaglia
David M. Ojcius

Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection, Chang-Chieh Chen, Sheng-Hui Tsai, Chia-Chen Lu, Shiau-Ting Hu, Ting-Shu Wu, Tsung-Teng Huang, Najwane Saïd-Sadier, David M. Ojcius, Hsin-Chih Lai
David M. Ojcius

An iterative strategy combining biophysical criteria and duration hidden Markov) models for structural predictions of Chlamydia trachomatis s66 promoters, Ronna R. Mallios, David M. Ojcius, David H. Ardell
David M. Ojcius

Association between coinfection of Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Treponema denticola and periodontal tissue destruction in chronic periodontitis, L. L. Chen, Y. M. Wu, J. Yan, W. L. Sun, Y. Z. Sun, David M. Ojcius
David M. Ojcius

An iron detection system determines bacterial swarming initiation and biofilm formation, Chuan-Sheng Lin, Yu-Huan Tsai, Chih-Jung Chang, Shun-Fu Tseng, Tseng-Ru Wu, Chia-Chen Lu, Ting-Shu Wu, Jang-Jih Lu, Jim-Tong Horng, Jan Martel, David M. Ojcius, Hsin-Chih Lai, John Ding-E. Young
David M. Ojcius

Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase, Najwane Saïd-Sadier, Eduardo V. Padilla, Gordon Langsley, David M. Ojcius
David M. Ojcius

Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Shuang Chen, Norika Chiba, V. Krishnan Ramanujan, Laurent Vergnes, David M. Ojcius, Moshe Arditi
David M. Ojcius

Characterization of severe fever with thrombocytopenia syndrome in rural regions of Zhejiang, China, Lei Zhang, Ling Ye, David M. Ojcius, Xiuyu Lou, Chengwei Wang, Cen Feng, Yi Sun, Zhongfa Wang, Shibo Li, Yanjun Zhang
David M. Ojcius

Characterization of host cell death induced by Chlamydia trachomatis, Songmin Ying, Silke F. Fischer, Matthew A. Pettengill, Debye Conte, Stefan A. Paschen, David M. Ojcius, Georg Hacker
David M. Ojcius

Characterization of a gene encoding two isoforms of a mitochondrial protein upregulated by cyclosporin A in activated T cells, Laurent Mascarell, Rodolphe Auger, Andres Alcover, David M. Ojcius, Thomas Jungas, Veronique Cadet-Daniel, Jean M. Kanellopoulos, Paolo Truffa-Bacchi
David M. Ojcius

Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein, Haiyan Dong, Ye Hu, Feng Xue, Dexter Sun, David M. Ojcius, Yafei Mao, Jie Yan
David M. Ojcius

Cytolytic and ion channel forming properties of the N-terminus of lymphocyte perforin, David M. Ojcius, Pedro M. Persechini, Li-Mou Zheng, Paulo C. Notaroberto, Sandro C. Adeodato, John Ding-E. Young
David M. Ojcius

Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia, Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frederic Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M. Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, Jose R. Regueiro, Hughes de Thé, Marie-Lise Gougeon, Mauro Piacentini, Guido Kroemer
David M. Ojcius

Creation of an immunodeficient HLA-transgenic mouse (HUMAMICE) and functional validation of human immunity after transfer of HLA-matched human cells, Yang Zeng, Bingrun Liu, Marie-Therese Rubio, Xinyue Wang, David M. Ojcius, Ruoping Tang, Antoine Durrbach, Zhitao Ru, Yusen Zhou, Yu-Chun Lone
David M. Ojcius

Distribution of endosomal, lysosomal and MHC markers in a monocytic cell line infected with Chlamydia psittaci, David M. Ojcius, Raymond Hellio, Alice Dautry-Varsat
David M. Ojcius

Detection and characterization of mineralo-organic nanoparticles in human kidneys, Tsui-Yin Wong, Cheng-Yeu Wu, Jan Martel, Cheng-Wei Lin, Fu-Yung Hsu, David M. Ojcius, Paul Y. Lin, John Ding-E. Young
David M. Ojcius

Development of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope protein, Zhitao Ru, Wenjun Xiao, Anthony Pajot, Zhihua Kou, Shihui Sun, Benard Maillere, Guangyu Zhao, David M. Ojcius, Yu-Chun Lone, Yusen Zhou
David M. Ojcius

Effect of Chlamydia trachomatis infection and subsequent TNFa secretion on apoptosis in the murine genital tract, Jean-Luc Perfettini, Toni Darville, Gabriel Gachelin, Philippe Souque, Michel Huerre, Alice Dautry-Varsat, David M. Ojcius
David M. Ojcius

Eosinophils from murine lamina propria induce differentiation of naïve T cells into regulatory T cells via TGF-β1 and retinoic acid, Hong-Hu Chen, Ai-Hua Sun, David M. Ojcius, Wei-Lin Hu, Yu-Mei Ge, Xu'ai Lin, Lan-Juan Li, Jian-Ping Pan, Jie Yan
David M. Ojcius

Enhancement of ATP levels and glucose metabolism during an infection by Chlamydia: NMR studies of living cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat
David M. Ojcius

Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator, Thomas Jungas, Iris Motta, Francis Duffieux, Pascale Fanen, Veronique Stoven, David M. Ojcius
David M. Ojcius

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota, Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Jan Martel, Yun-Fei Ko, David M. Ojcius, Shun-Fu Tseng, Tsung-Ru Wu, Yi-Yuan Margaret Chen, John Ding-E. Young, Hsin-Chih Lai
David M. Ojcius

Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Verissa M. Lam, Bhavni Singh, Matthew A. Pettengill, Fraser Soares, Ivan Tattoli, Simone Lipinski, Stephen E. Girardin, Philip Rosenstiel, David M. Ojcius
David M. Ojcius

Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection, Claire Séror, Marie-Therese Melki, Frederic Subra, Syed Qasim Raza, Marlene Bras, Hela Saïdi, Roberta Nardacci, Laurent Voisin, Audrey Paoletti, Frederic Law, Isabelle Martins, Alessandra Amendola, Ali A. Abdul-Sater, Fabiola Ciccosanti, Olivier Delelis, Florence Niedergang, Sylvain Thierry, Najwane Said-Sadier, Christophe Lamaze, Didier Métivier, Jerome Estaquier, Gian Maria Fimia, Laura Falasca, Rita Casetti, Nazanine Modjtahedi, Jean M. Kanellopoulos, Jean-Francois Mouscadet, David M. Ojcius, Mauro Piacentini, Marie-Lise Gougeon, Guido Kroemer, Jean-Luc Perfetini
David M. Ojcius

Hirsutella sinensis mycelium suppresses interleukin-1b and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes, Tsung-Teng Huang, Kowit-Yu Chong, David M. Ojcius, Yi-Hui Wu, Yun-Fei Ko, Cheng-Yeu Wu, Jan Martel, Chia-Chen Lu, Hsin-Chih Lai, John Ding-E. Young
David M. Ojcius

Identification of Leptospira interrogans phospholipase C as a novel virulence factor responsible for intracellular free calcium ion elevation during macrophage death, Jing-Fang Zhao, Hong-Hu Chen, David M. Ojcius, Xin Zhao, Dexter Sun, Yu-Mei Ge, Lin-Li Zheng, Xu'ai Lin, Lan-Juan Li, Jie Yan
David M. Ojcius

Hepatitis C virus frameshift/alternate reading frame protein suppresses interferon responses mediated by pattern recognition receptor retinoic-acid-inducible gene-I, Seung Bum Park, Scott Seronello, Wasima Mayer, David M. Ojcius
David M. Ojcius

Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo, Tsung-Teng Huang, Hsin-Chih Lai, Yun-Fei Ko, David M. Ojcius, Ying-Wei Lan, Jan Martel, John Ding-E. Young, Kowit-Yu Chong
David M. Ojcius

Identification of CD24 as a cancer stem cell marker in human nasopharyngeal carcinoma, Chun-Hung Yang, Hui-Ling Wang, Yi-Sheng Lin, K. P. Shravan Kumar, Hung-Chi Lin, Chih-Jung Chang, Chia-Chen Lu, Tsung-Teng Huang, Jan Martel, David M. Ojcius, Yu-Sun Chang, John Ding-E. Young, Hsin-Chih Lai
David M. Ojcius

Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L(2)) and D lineages, Naraporn Somboonna, Raymond Wan, David M. Ojcius, Matthew A. Pettengill, Sandeep J. Joseph, Alexander Chang, Ray Hsu, Timothy D. Read, Deborah Dean
David M. Ojcius

Purification and ligand binding of a soluble class I MHC molecule consisting of the first three domains of H-2Kd fused to b2-microglobulin expressed in the baculovirus/insect cell system, Francois Godeau, Immanuel F. Luescher, David M. Ojcius, Cecile Saucier, Estelle Mottez, Lucien Cabanie, Philippe Kourilsky
David M. Ojcius

Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival, Philippe Verbeke, Lynn Welter-Stahl, S. Ying, J. Hansen, Georg Hacker, Toni Darville, David M. Ojcius
David M. Ojcius

Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis, I-Che Chung, Chun-Nan OuYang, Sheng-Ning Yuan, Hsin-Pai P. Li, Jeng-Ting Chen, Hui-Ru Shieh, Yu-Jen Chen, David M. Ojcius, Ching-Liang Chu, Jau-Song Yu, Yu-Sun Chang, Lih-Chyang Chen
David M. Ojcius

Role of Bcl-2 family members in caspase-independent apoptosis due to Chlamydia infection, Jean-Luc Perfettini, John C. Reed, Nicole Israel, Jean-Claude Martinou, Alice Dautry-Varsat, David M. Ojcius
David M. Ojcius

Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X4 receptors, Matthew A. Pettengill, Camila Marques-da-Silva, Maria Luisa Avila, Verissa W. Lam, Ikechukwu Ollawa, Ali Abdul-Sater, Robson Coutinho-Silva, Georg Hacker, David M. Ojcius, Suellen d'Arc dos Santos Oliveira
David M. Ojcius

Separate metabolic pathways leading to DNA fragmentation and apoptotic nuclear chromatin condensation, D. Sun, Shibo Jiang, Li-Mou Zheng, David M. Ojcius, John Ding-E. Young
David M. Ojcius

Role of proapoptotic BAX in propagation of Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis) and the host inflammatory response, Jean-Luc Perfettini, David M. Ojcius, Charles W. Andrews Jr., Stanley J. Korsmeyer, Roger G. Rank, Toni Darville
David M. Ojcius

The microtubule-associated protein, EB1, links AIM2 inflammasomes with autophagy-dependent secretion, Li-Jie Wang, Hsin-Yi Huang, Meng-Pin Huang, Willisa Liou, Ya-Ting Chang, Chih-Ching Wu, David M. Ojcius, Yu-Sun Chang
David M. Ojcius

The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages, Tsung-Teng Huang, David M. Ojcius, John Ding-E. Young, Yi-Hui Wu, Yun-Fei Ko, Tsui-Yin Wong, Cheng-Yeu Wu, Chia-Chen Lu, Hsin-Chih Lai
David M. Ojcius

Susceptibility of Chlamydia trachomatis to the excipient hydroxy-ethylcellulose: pH and concentration dependence of antimicrobial activity, Ali A. Abdul-Sater, David M. Ojcius, M. P. Meyer
David M. Ojcius

TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans, Mufadhal Al-Kuhlani, James Rothchild, Sukumar Pal, Luis M. de la Maza, Sander Ouberg, Servaas A. Morré, Deborah Dean, David M. Ojcius
David M. Ojcius

The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors, Matthew A. Pettengill, Verissa W. Lam, David M. Ojcius
David M. Ojcius

pH and calcium dependence of hemolysis due to Rickettsia prowazekii: comparison with phospholipase activity, David M. Ojcius, M. Thibon, C. Mounier, Alice Dautry-Varsat
David M. Ojcius

Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface, Colette Kanellopoulos-Langevin, Stephane M. Caucheteux, Philippe Verbeke, David M. Ojcius
David M. Ojcius

The pathological effects of CCR2+ inflammatory monocytes are amplified by an IFNAR1-triggered chemokine feedback loop in highly pathogenic influenza infection, Sue-Jane Lin, Ming Lo, Rei-Lin Kuo, Shin-Ru Shih, David M. Ojcius, Jean Lu, Chien-Kuo Lee, Hui-Chen Chen, Meei Yun Lin, Chuen-Miin Leu, Chia-Ni Lin, Ching-Hwa Tsai
David M. Ojcius

Tumour inflammasome-derived IL-1b recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma, Lih-Chyang Chen, Li-Jie Wang, Nang-Ming Tsang, David M. Ojcius, Chia-Chen Chen, Chun-Nan OuYang, Chuen Hsueh, Ying Liang, Kai-Ping Chang, Chiu-Chin Chen, Yu-Sun Chang
David M. Ojcius

Inactivation of Disease-Causing Nonresistant and Antibiotic-resistant Trichomonas vaginalis Strains by Food-Compatible Plant Extracts, Sabrina M. Noritake, Jenny Liu, Sierra Kanetake, Carol E. Levin, Christina Tam, Luisa W. Cheng
Pacific Undergraduate Research and Creativity Conference (PURCC)

Antiprotozoal Effects of the Tomato Tetrasaccharide Glycoalkaloid Tomatine and the Aglycone Tomatidine on Mucosal Trichomonads, Jenny Chen Liu, Sierra Kanetake, Yun-Hsuan Wu
Pacific Undergraduate Research and Creativity Conference (PURCC)

MicroRNAs Modulate Pathogenesis Resulting from Chlamydial Infection in Mice, Laxmi Yeruva, S. Pouncey, Michael R. Eledge, Sudeepa Bhattacharya, Chunqiao Luo, Erin W. Weatherford, David M. Ojcius, Roger G. Rank
All Dugoni School of Dentistry Faculty Articles

Anti-obesogenic and antidiabetic effects of plants and mushrooms, Jan Martel, David M. Ojcius, Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Shun-Fu Tseng, Hsin-Chih Lai, John Ding-E. Young, Yun-Fei Ko
All Dugoni School of Dentistry Faculty Articles

Isolation, Culture and Characterization of Hirsutella sinensis Mycelium from Caterpillar Fungus Fruiting Body, Yun-Fei Komi, Jian-Ching Liau, Chien-Sheng Lee, Chen-Yaw Chiu, Jan Martel, Chuan-Sheng Lin, Shan-Fu Tseng, David M. Ojcius, Chia-Chen Lu, Hsin-Chih Lai, John Ding-E. Young
All Dugoni School of Dentistry Faculty Articles

An iron detection system determines bacterial swarming initiation and biofilm formation, Chuan-Sheng Lin, Yu-Huan Tsai, Chih-Jung Chang, Shun-Fu Tseng, Tseng-Ru Wu, Chia-Chen Lu, Ting-Shu Wu, Jang-Jih Lu, Jim-Tong Horng, Jan Martel, David M. Ojcius, Hsin-Chih Lai, John Ding-E. Young
All Dugoni School of Dentistry Faculty Articles

Nucleoside-Diphosphate-Kinase of P. gingivalis is Secreted from Epithelial Cells In the Absence of a Leader Sequence Through a Pannexin-1 Interactome, Kalina Atanasova, Jungnam Lee, JoAnn Roberts, Kyulim Lee, David M. Ojcius, Özlem Yilmaz
All Dugoni School of Dentistry Faculty Articles

Danger signals, inflammasomes, and the intricate lives of chlamydiae, Matthew A. Pettengill, Ali A. Abdul-Sater, Robson Coutinho-Silva, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

Role of epigenetics in modulation of immune response at the junction of host-pathogen interaction and danger molecule signaling., Ana Carolina Morandini, Ana Carolina Morandini, Ana Carolina Morandini, Carlos Ferreira Santos, Özlem Yilmaz
Ana Carolina Morandini

Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis, I-Che Chung, Chun-Nan OuYang, Sheng-Ning Yuan, Hsin-Pai P. Li, Jeng-Ting Chen, Hui-Ru Shieh, Yu-Jen Chen, David M. Ojcius, Ching-Liang Chu, Jau-Song Yu, Yu-Sun Chang, Lih-Chyang Chen
All Dugoni School of Dentistry Faculty Articles

Purinergic signaling during Porphyromonas gingivalis infection, Cássio Luiz Coutinho Almeida-da-Silva, Ana Carolina Morandini, David M. Ojcius, Robson Coutinho-Silva, Henning Ulrich
All Dugoni School of Dentistry Faculty Articles

Purinergic signaling during Porphyromonas gingivalis infection., Cássio Luiz Coutinho Almeida-da-Silva, Ana Carolina Morandini, Henning Ulrich, David M. Ojcius, Robson Coutinho-Silva
David M. Ojcius

Purinergic signaling during Porphyromonas gingivalis infection., Cássio Luiz Coutinho Almeida-da-Silva, Ana Carolina Morandini, Ana Carolina Morandini, Henning Ulrich, David M. Ojcius, David M. Ojcius, Robson Coutinho-Silva
Ana Carolina Morandini

Fusobacterium nucleatum infection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1β and the danger signals ASC and HMGB1, F. Q. Bui, L. Johnson, JoAnn Roberts, S. C. Hung, J. Lee, K. R. Atanasova, P. R. Huang, Özlem Yilmaz, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

Hepatitis C virus frameshift/alternate reading frame protein suppresses interferon responses mediated by pattern recognition receptor retinoic-acid-inducible gene-I, Seung Bum Park, Scott Seronello, Wasima Mayer, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity, Chia-Chen Lu, Ya-Jing Hsu, Chih-Jung Chang, Chuan-Sheng Lin, Jan Martel, David M. Ojcius, Yun-Fei Ko, Hsin-Chih Lai, John Ding-E. Young
All Dugoni School of Dentistry Faculty Articles

Alternative functions for the multifarious inflammasome, Jan Martel, Hsin-Chih Lai, Yun-Fei Ko, John Ding-E. Young, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

Pretreatment with a heat-killed probiotic modulates monocyte chemoattractant protein-1 and reduces the pathogenicity of influenza and enterovirus 71 infections, M. F. Chen, K. F. Weng, S. Y. Huang, Y. C. Liu, S. N. Tseng, David M. Ojcius, S. R. Shih
All Dugoni School of Dentistry Faculty Articles

Is the inflammasome relevant for epithelial cell function?, Patricia T. Santana, Jan Martel, Hsin-Chih Lai, Jean-Luc Perfettini, Jean M. Kanellopoulos, John Ding-E. Young, Robson Coutinho-Silva, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

Modulation of host immune response by Bacteroides fragilis polysaccharides: a review of recent observations, Chih-Jung Chang, Chuan-Sheng Lin, Jan Martel, David M. Ojcius, W. F. Lai, Chia-Chen Lu, Yun-Fei Ko, John Ding-E. Young, Hsin-Chih Lai
All Dugoni School of Dentistry Faculty Articles

Nanoparticle conversion to biofilms: in vitro demonstration using serum-derived mineralo-organic nanoparticles, Tsui-Yin Wong, Hsin-Hsin Peng, Cheng-Yeu Wu, Jan Martel, David M. Ojcius, Fu-Yung Hsu, John Ding-E. Young
All Dugoni School of Dentistry Faculty Articles

Intracellular bacterial pathogens: a reemerging field of research rich with breakthroughs and opportunities, Gilbert Greub, Chantal P. Bleeker-Rovers, Jason Carlyon, Pierre-Edouard Fournier, David M. Ojcius, Mirja Puolakkainen
All Dugoni School of Dentistry Faculty Articles

Eosinophils from murine lamina propria induce differentiation of naïve T cells into regulatory T cells via TGF-β1 and retinoic acid, Hong-Hu Chen, Ai-Hua Sun, David M. Ojcius, Wei-Lin Hu, Yu-Mei Ge, Xu'ai Lin, Lan-Juan Li, Jian-Ping Pan, Jie Yan
All Dugoni School of Dentistry Faculty Articles

Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo, Tsung-Teng Huang, Hsin-Chih Lai, Yun-Fei Ko, David M. Ojcius, Ying-Wei Lan, Jan Martel, John Ding-E. Young, Kowit-Yu Chong
All Dugoni School of Dentistry Faculty Articles

Detection and characterization of mineralo-organic nanoparticles in human kidneys, Tsui-Yin Wong, Cheng-Yeu Wu, Jan Martel, Cheng-Wei Lin, Fu-Yung Hsu, David M. Ojcius, Paul Y. Lin, John Ding-E. Young
All Dugoni School of Dentistry Faculty Articles

MERS – a cautionary tale, Sophia Hafner, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

A new frontier: oral microbes without borders, Özlem Yilmaz, David M. Ojcius
All Dugoni School of Dentistry Faculty Articles

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota, Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Jan Martel, Yun-Fei Ko, David M. Ojcius, Shun-Fu Tseng, Tsung-Ru Wu, Yi-Yuan Margaret Chen, John Ding-E. Young, Hsin-Chih Lai
All Dugoni School of Dentistry Faculty Articles

Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase, Larry Johnson, Kalina R. Atanasova, Phuong Q. Bui, Jungnam Lee, Shu-Chen Hung, Özlem Yilmaz, David M. Ojcius
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Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages leading to the release of pro-inflammatory cytokines, Bruce J. Shenker, David M. Ojcius, Lisa P. Walker, Ali Zekavat, Monika Damek Scuron, Kathleen Boesze-Battaglia
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Introduction to miniseries on DNA and cancer, J. M. Kanellopoulos, David M. Ojcius
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Stimulation and repression of cancer development by caveolae and nitric oxide, C. M. Blouin, David M. Ojcius
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The histone deasetylase HDAC1 expression in human periodontitis – preliminary results, Ana Carolina Morandini, E. J. Franco, Erivan Schnaider Ramos-Junior, A. A. Pedra, F. B. Andrade, Carlos Ferreira Santos
Ana Carolina Morandini

Mushrooms – from cuisine to clinic, Jan Martel, David M. Ojcius, Hsin-Chih Lai, John Ding-E. Young
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A dual role for P2X7 receptor during Porphyromonas gingivalis infection, E. S. Ramos-Junior, Ana Carolina Morandini, Cassio Almeida-da-Silva, E. J. Franco, J. Potempa, K. A. Nguyen, A. C. Oliveira, D. S. Zamboni, David M. Ojcius, J. Scharfstein, Robson Coutinho-Silva
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Activation of the NLRP3 inflammasome by vault nanoparticles expressing a chlamydial epitope, Ye Zhu, Janina Jiang, Najwane Said-Sadier, Gale Boxx, Cheryl Champion, Ashley Tetlow, Valerie A. Kickhoefer, Leonard H. Rome, David M. Ojcius, Kathleen A. Kelly
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NK cells kill mycobacteria directly by releasing perforin and granulysin, Chia-Chen Lu, Ting-Shu Wu, Ya-Jing Hsu, Chih-Jung Chang, Chuan-Sheng Lin, Ju-Hsin Chia, Tsu-Lan Wu, Tsung-Teng Huang, Jan Martel, David M. Ojcius, John Ding-E. Young, Hsin-Chih Lai
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The pathological effects of CCR2+ inflammatory monocytes are amplified by an IFNAR1-triggered chemokine feedback loop in highly pathogenic influenza infection, Sue-Jane Lin, Ming Lo, Rei-Lin Kuo, Shin-Ru Shih, David M. Ojcius, Jean Lu, Chien-Kuo Lee, Hui-Chen Chen, Meei Yun Lin, Chuen-Miin Leu, Chia-Ni Lin, Ching-Hwa Tsai
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Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion, Ana Carolina Morandini, E. S. Ramos-Junior, J. Potempo, K. A. Nguyen, A. C. Oliveira, M. Bellio, David M. Ojcius, J. Scharfstein, Robson Coutinho-Silva
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Is the hoopla over CPAF justified?, Georg Hacker, Dagmar Heuer, David M. Ojcius
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A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells, Kuo-Feng Weng, Chuan-Tien Hung, Po-Ting Hsieh, Mei-Ling L. Li, Guang-Wu Chen, Yu-An Kung, Peng-Nien Huang, Rei-Lin Kuo, Li-Lien Chen, Jing-Yi Lin, Robert Yung-Liang Wang, Shu-Jen Chen, Petrus Tang, Jim-Tong Horng, Hsing-I Huang, Jen-Ren Wang, David M. Ojcius, Gary Brewer, Shin-Ru Shih
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Characterization of severe fever with thrombocytopenia syndrome in rural regions of Zhejiang, China, Lei Zhang, Ling Ye, David M. Ojcius, Xiuyu Lou, Chengwei Wang, Cen Feng, Yi Sun, Zhongfa Wang, Shibo Li, Yanjun Zhang
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Chlamydia trachomatis infection increases the expression of inflammatory tumorigenic cytokines and chemokines as well as components of the Toll-like receptor and NF-κB pathways in human prostate epithelial cells, H. Sellami, Najwene Saïd-Sadier, A. Znazen, R. Gdoura, David M. Ojcius, A. Hammami
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Valley fever: danger lurking in a dust cloud, Larry Johnson, Erin M. Gaab, Javier Sanchez, Phuong Q. Bui, Clarissa J. Nobile, Katrina K. Hoyer, Michael W. Peterson, David M. Ojcius
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The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome, Tsung-Teng Huang, Sian-Pu Wu, Kowit-Yu Chong, David M. Ojcius, Yun-Fei Ko, Yi-Hui Wu, Cheng-Yeu Wu, Chia-Chen Lu, Jan Martel, John Ding-E. Young, Hsin-Chih Lai
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The microtubule-associated protein, EB1, links AIM2 inflammasomes with autophagy-dependent secretion, Li-Jie Wang, Hsin-Yi Huang, Meng-Pin Huang, Willisa Liou, Ya-Ting Chang, Chih-Ching Wu, David M. Ojcius, Yu-Sun Chang
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MicroRNA-146a and microRNA-155 show tissue-dependent expression in dental pulp, gingival and periodontal ligament fibroblasts in vitro, Carla Renata Sipert, Ana Carolina Morandini, Thiago José Dionísio, Alexander J. Trachtenberg, Winston P. Kuo, Carlos Ferreira Santos
Ana Carolina Morandini

Identification of CD24 as a cancer stem cell marker in human nasopharyngeal carcinoma, Chun-Hung Yang, Hui-Ling Wang, Yi-Sheng Lin, K. P. Shravan Kumar, Hung-Chi Lin, Chih-Jung Chang, Chia-Chen Lu, Tsung-Teng Huang, Jan Martel, David M. Ojcius, Yu-Sun Chang, John Ding-E. Young, Hsin-Chih Lai
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Identification of collagenase as a critical virulence factor for invasiveness and transmission of pathogenic Leptospira species, Kokouvi Kassegne, Weilin Hu, David M. Ojcius, Dexter Sun, Yu-Mei Ge, Jinfang Zhao, X. Frank Yang, Lanjuan Li, Jie Yan
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TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans, Mufadhal Al-Kuhlani, James Rothchild, Sukumar Pal, Luis M. de la Maza, Sander Ouberg, Servaas A. Morré, Deborah Dean, David M. Ojcius
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Methyl-accepting chemotaxis proteins 3 and 4 are responsible for Campylobacter jejuni chemotaxis and jejuna colonization in mice in response to sodium deoxycholate, Zhifeng Li, Hongqiang Lou, David M. Ojcius, Aihua Sun, Dexter Sun, Jinfang Zhao, Xu'ai Lin, Jie Yan
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Another year of microbial pathogens and the host immune response, David M. Ojcius
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Impact of the gut microbiota, prebiotics, and probiotics on human health and disease, C. S. Lin, Chih-Jung Chang, Chau-Ching Liu, Jan Martel, David M. Ojcius, Yun-Fei Kourilsky, John Ding-E. Young, Hsin-Chih Lai
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cis-Resveratrol produces anti-inflammatory effects by inhibiting canonical and non-canonical inflammasomes in macrophages, Tsung-Teng Huang, Hsin-Chih Lai, Young-Bin Chen, Lih-Geeng Chen, Yi-Hui Wu, Yun-Fei Kourilsky, Chia-Chen Lu, Chih-Jung Chang, Cheng-Yeu Wu, Jan Martel, David M. Ojcius, Kowit-Yu Chong, John Ding-E. Young
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In vitro regulation of CCL3 and CXCL12 by bacterial by-products is dependent on site of origin of human oral fibroblasts, Carla Renata Sipert, Ana Carolina Morandini, Thiago José Dionísio, Maria Aparecida de Andrade Moreira Machado, Sandra Helena Penha de Oliveira, Ana Paula Campanelli, Winston Patrick Kuo, Carlos Ferreira Santos
Ana Carolina Morandini

Systemic use of antibiotics as adjuvants for chronic periodontitis: a literature review, L. S. F. Roberto, Anne Carolina E. Leite, E. J. Franco, P. P. Costa, Ana Carolina Morandini
Ana Carolina Morandini

A path forward for the chlamydial virulence factor CPAF, Turner A. Conrad, Zhangsheng Yang, David M. Ojcius, Guangming Zhong
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Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China, Lei Zhang, Jie Yan, David M. Ojcius, Huakun Lv, Ziping Miao, Yin Chen, Yanjun Zhang, Jvying Yan
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CD1d-restricted NKT cells modulate placental and uterine leukocyte populations during chlamydial infection in mice, Mohamed Habbeddine, Philippe Verbeke, Christiane Delarbre, Rene Moutier, Stephane Prieto, David M. Ojcius, Colette Kanellopoulos-Langevin
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p53 signalling controls cell cycle arrest and caspase-independent apoptosis in macrophages infected with pathogenic Leptospira species, W. Huang, Yu-Mei Ge, David M. Ojcius, Dexter Sun, H. Dong, X. F. Yang, Jie Yan
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Identification of Leptospira interrogans phospholipase C as a novel virulence factor responsible for intracellular free calcium ion elevation during macrophage death, Jing-Fang Zhao, Hong-Hu Chen, David M. Ojcius, Xin Zhao, Dexter Sun, Yu-Mei Ge, Lin-Li Zheng, Xu'ai Lin, Lan-Juan Li, Jie Yan
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Membrane vesicles nucleate mineralo-organic nanoparticles and induce carbonate apatite precipitation in human body fluids, Cheng-Yeu Wu, Jan Martel, Wei-Yun Cheng, Chao-Chih He, David M. Ojcius, John Ding-E. Young
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P2X4 assembles with P2X7 and pannexin-1 in gingival epithelial cells and modulates reactive oxygen species production and inflammasome activation, Shu-Chen Hung, Chul Hee Choi, Najwane Said-Sadier, Larry Johnson, Kalina Rosenova Atanasova, Hanen Sellami, Özlem Yilmaz, David M. Ojcius
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Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7 receptor / NADPH-oxidase signaling and contributes to persistence, C. H. Choi, R. Spooner, J. DeGuzman, T. Koutouzis, David M. Ojcius, Özlem Yilmaz
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Characterizing the intracellular distribution of metabolites in intact Chlamydia-infected cells by Raman and two-photon microscopy, Marta Szaszak, Jiun Chiun Chang, Weinan Leng, Jan Rupp, David M. Ojcius, Anne Myers Kelley
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Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin, Chih-Jung Chang, Yi-Yuan M. Chen, Chia-Chen Lu, Chuan-Sheng Lin, Jan Martel, Sheng-Hui Tsai, Yun-Fei Ko, Tsung-Teng Huang, David M. Ojcius, John Ding-E. Young, Hsin-Chih Lai
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Transcription factor complex AP-1 mediates inflammation initiated by Chlamydia pneumoniae infection, A. Wang, M. Al-Kuhlani, S. C. Johnston, David M. Ojcius, J. Chou, D. Dean
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Hirsutella sinensis mycelium suppresses interleukin-1b and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes, Tsung-Teng Huang, Kowit-Yu Chong, David M. Ojcius, Yi-Hui Wu, Yun-Fei Ko, Cheng-Yeu Wu, Jan Martel, Chia-Chen Lu, Hsin-Chih Lai, John Ding-E. Young
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Interaction between Immune System and Mesenchymal Stem Cells in Endodontic Pathoses and Clinical Relevance, Julian Leprince, BD Zeitlin, M Tolar, Ove Peters
Ove Peters

Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X4 receptors, Matthew A. Pettengill, Camila Marques-da-Silva, Maria Luisa Avila, Verissa W. Lam, Ikechukwu Ollawa, Ali Abdul-Sater, Robson Coutinho-Silva, Georg Hacker, David M. Ojcius, Suellen d'Arc dos Santos Oliveira
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Tumour inflammasome-derived IL-1b recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma, Lih-Chyang Chen, Li-Jie Wang, Nang-Ming Tsang, David M. Ojcius, Chia-Chen Chen, Chun-Nan OuYang, Chuen Hsueh, Ying Liang, Kai-Ping Chang, Chiu-Chin Chen, Yu-Sun Chang
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Physicochemical and biological properties of biomimetic mineralo-protein nanoparticles formed spontaneously in biological fluids, Hsin-Hsin Peng, Cheng-Yeu Wu, David Young, Jan Martel, Andrew Young, David M. Ojcius, Yu-Hsiu Lee, John Ding-E. Young
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Role of extracellular nucleotides in the immune response against intracellular bacteria and protozoan parasites, Robson Coutinho-Silva, David M. Ojcius
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Rapid and sensitive identification of RNA from the emerging pathogen, coxsackievirus A6, Lei Zhang, Xinying Wang, Yanjun Zhang, Liming Gong, Haiyan Mao, Cen Feng, David M. Ojcius, Jie Yan
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Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol, Hsin-Chih Lai, Chih-Jung Chang, Chun-Hung Yang, Ya-Jing Hsu, Chang-Chieh Chen, Chuan-Sheng Lin, Yu-Huan Tsai, Tsung-Teng Huang, David M. Ojcius, Ying-Huang Tsai, Chia-Chen Lu
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Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells, Matthew A. Pettengill, Verissa W. Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, David M. Ojcius
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Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways, Huan Wang, Yifei Hu, David M. Ojcius, X. Frank Yang, Chenglin Zhang, Shibiao Ding, Xu'ai Lin, Jie Yan
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Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes, Li-Jie Wang, Chia-Wei Hsu, Chiu-Chin Chen, Ying Liang, Lih-Chyang Chen, David M. Ojcius, Ngan-Ming Tsang, Chuen Hsueh, Chih-Ching Wu, Yu-Sun Chang
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The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages, Tsung-Teng Huang, David M. Ojcius, John Ding-E. Young, Yi-Hui Wu, Yun-Fei Ko, Tsui-Yin Wong, Cheng-Yeu Wu, Chia-Chen Lu, Hsin-Chih Lai
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Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection, Chang-Chieh Chen, Sheng-Hui Tsai, Chia-Chen Lu, Shiau-Ting Hu, Ting-Shu Wu, Tsung-Teng Huang, Najwane Saïd-Sadier, David M. Ojcius, Hsin-Chih Lai
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The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals, Lei Zhang, Chenglin Zhang, David M. Ojcius, Dexter Sun, Jinfang Zhao, Xu'ai Lin, Liwei Li, Lanjuan Li, Jie Yan
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Jargalsaikhan Dagvadori, Norika Chiba, Shuang Chen, V. Krishnan Ramanujan, Andrea J. Wolf, Laurent Vergnes, David M. Ojcius, Altan Rentsendorj, Mario Vargas, Candace Guerrero, Yinsheng Wang, Katherine A. Fitzgerald, David M. Underhill, Terrence Town, Moshe Arditi
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Development of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope protein, Zhitao Ru, Wenjun Xiao, Anthony Pajot, Zhihua Kou, Shihui Sun, Benard Maillere, Guangyu Zhao, David M. Ojcius, Yu-Chun Lone, Yusen Zhou
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Alarmins, inflammasomes and immunity, Najwane Saïd-Sadier, David M. Ojcius
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Infection with Leishmania amazonensis upregulates purinergic receptor expressionand induces host-cell susceptibility to UTP-mediated apoptosis, Camila Marques-da-Silva, M. M. Chaves, S. P. Chaves, V. R. Figliuolo, J. R. Meyer-Fernandes, S. Corte-Real, C. Lameu, H. Ulrich, David M. Ojcius, B. Rossi-Bergmann, Robson Coutinho-Silva
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Altered pathogenicity for seasonal influenza virus by single reassortment of the RNP genes derived from the 2009 pandemic influenza virus, Erh-Fang Hsieh, Sue-Jane Lin, Chee-Keng Mok, Guang-Wu Chen, Chih-Heng Huang, Yeau-Ching Wang, Tzu-Chun Chen, Chi-Jene Chen, David M. Ojcius, Shin-Ru Shih
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Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection, Claire Séror, Marie-Therese Melki, Frederic Subra, Syed Qasim Raza, Marlene Bras, Hela Saïdi, Roberta Nardacci, Laurent Voisin, Audrey Paoletti, Frederic Law, Isabelle Martins, Alessandra Amendola, Ali A. Abdul-Sater, Fabiola Ciccosanti, Olivier Delelis, Florence Niedergang, Sylvain Thierry, Najwane Said-Sadier, Christophe Lamaze, Didier Métivier, Jerome Estaquier, Gian Maria Fimia, Laura Falasca, Rita Casetti, Nazanine Modjtahedi, Jean M. Kanellopoulos, Jean-Francois Mouscadet, David M. Ojcius, Mauro Piacentini, Marie-Lise Gougeon, Guido Kroemer, Jean-Luc Perfetini
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Serum-derived nanoparticles: de novo generation and growth in vitro, and internalization by mammalian cells in culture, Hsin-Hsin Peng, Jan Martel, Yu-Hsiu Lee, David M. Ojcius, John Ding-E. Young
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Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Shuang Chen, Norika Chiba, V. Krishnan Ramanujan, Laurent Vergnes, David M. Ojcius, Moshe Arditi
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Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L(2)) and D lineages, Naraporn Somboonna, Raymond Wan, David M. Ojcius, Matthew A. Pettengill, Sandeep J. Joseph, Alexander Chang, Ray Hsu, Timothy D. Read, Deborah Dean
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Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin, Tsung-Teng Huang, Fu-Guo Liu, Chia-Fong Wei, Chia-Chen Lu, Chang-Chieh Chen, Hung-Chi Lin, David M. Ojcius, Hsin-Chih Lai
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Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages, Camila Marques-da-Silva, Geoffrey Burnstock, David M. Ojcius, Robson Coutinho-Silva
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Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Verissa M. Lam, Bhavni Singh, Matthew A. Pettengill, Fraser Soares, Ivan Tattoli, Simone Lipinski, Stephen E. Girardin, Philip Rosenstiel, David M. Ojcius
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Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Eduardo V. Padilla, David M. Ojcius
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Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells, L. Yao, C. Jermanus, B. Barbetta, C. Choi, Philippe Verbeke, David M. Ojcius, Özlem Yilmaz
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Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase, Najwane Saïd-Sadier, Eduardo V. Padilla, Gordon Langsley, David M. Ojcius
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ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis, Özlem Yilmaz, Ali A. Abdul-Sater, L. Yao, T. Koutouzis, Matthew A. Pettengill, David M. Ojcius
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Microbes and Infection: past, present and future, David M. Ojcius, Stefan H. E. Kaufmann
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Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin, Shijun Li, David M. Ojcius, Sumei Liao, Liwei Li, Feng Xue, Haiyan Dong, Jie Yan
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Chikungunya fever: re-emergence of an old disease, Lisa F. P. Ng, David M. Ojcius
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Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai, Sumei Liao, Ai-Hua Sun, David M. Ojcius, Senlin Wu, Jinfang Zhao, Jie Yan
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Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity, Dongjiao Luo, Feng Xue, David M. Ojcius, Jinfang Zhao, Ya-Fei Mao, Liwei Li, Xu'ai Lin, Jie Yan
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The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors, Matthew A. Pettengill, Verissa W. Lam, David M. Ojcius
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Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis, Ali A. Abdul-Sater, Evonne Koo, Georg Hacker, David M. Ojcius
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An iterative strategy combining biophysical criteria and duration hidden Markov) models for structural predictions of Chlamydia trachomatis s66 promoters, Ronna R. Mallios, David M. Ojcius, David H. Ardell
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The oral microbiota: living with a permanent guest, Maria Avila, David M. Ojcius, Ozlem Yilmaz
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The P2X7 receptor and intracellular pathogens: a continuing struggle, Robson Coutinho-Silva, Gladys Corrêa, Ali A. Abdul-Sater, David M. Ojcius
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Leptospira interrogans induces apoptosis in macrophages via caspase-8- and -3-dependent pathways, Dandan Jin, David M. Ojcius, Dexter Sun, Haiyan Dong, Yihui Luo, Yafei Mao, Jie Yan
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Inflammasomes bridge signalling between pathogen identification and the immune response, Ali A. Abdul-Sater, Najwene Saïd-Sadier, David M. Ojcius, O. Yilmaz, Kathy A. Kelly
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Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNg in human epithelial cells, L. Welter-Stahl, C. M. da Silva, Julieta Schachter, Pedro M. Persechini, H. S. Souza, David M. Ojcius, Robson Coutinho-Silva
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The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope, Jean-Luc Perfettini, Roberta Nardacci, C. Séror, M. Bourouba, F. Subra, L. Gros, Gwenola Manic, A. Amendola, P. Masdehors, F. Rosselli, David M. Ojcius, C. Auclair, H. de Thé, M. L. Gougeon, M. Piacentini, G. Kroemer
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Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein, Haiyan Dong, Ye Hu, Feng Xue, Dexter Sun, David M. Ojcius, Yafei Mao, Jie Yan
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Recombinant SpaO and H1a as immunogens for protection of mice from lethal infection with Salmonella paratyphi A: implications for rational design of typhoid fever vaccines, Ping Ruan, Xiao-Ping Xia, Dexter Sun, David M. Ojcius, Ya-Fei Yao, Wen-Yue Yue, Jie Yan
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Premature apoptosis of Chlamydia-infected cells disrupts chlamydial development, Songmin Ying, Matthew A. Pettengill, E. Ray Latham, Axel Walch, David M. Ojcius, Georg Hacker
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The book reopened on infectious diseases, Maria Avila, Najwane Said, David M. Ojcius
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Cytopathicity of Chlamydia is largely reproduced by expression of a single chlamydial protease, Stefan A. Paschen, Jan G. Christian, Juliane Vier, Franziska Schmidt, Axel Walch, David M. Ojcius, Georg Hacker
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Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia, Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frederic Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M. Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, Jose R. Regueiro, Hughes de Thé, Marie-Lise Gougeon, Mauro Piacentini, Guido Kroemer
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ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X(7)-mediated host-cell apoptosis, Özlem Yilmaz, L. Yao, K. Maeda, T. M. Rose, E. L. Lewis, M. Duman, R. J. Lamont, David M. Ojcius
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Susceptibility of Chlamydia trachomatis to the excipient hydroxy-ethylcellulose: pH and concentration dependence of antimicrobial activity, Ali A. Abdul-Sater, David M. Ojcius, M. P. Meyer
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Comparison of invasion of fibroblasts and macrophages by high- and low-virulence Leptospira strains: colonization of the host-cell nucleus and induction of necrosis by the virulent strain, L. Li, David M. Ojcius, J. Yan
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Correlation between infections with different genotypes of human cytomegalovirus and Epstein-Barr virus in subgingival samples and the periodontal status of patients, Yan-Min Wu, Jie Yan, David M. Ojcius, Li-Li Chen, Zhi-Yuan Gu, Jian-Peng Pan
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The Th1 immune response against HIV-1 Gag p24-derived peptides in mice expressing HLA-A02.01 and HLA-DR1, Anthony Pajot, Aurelie Schnuriger, Arnaud Moris, Audrey Rodallec, David M. Ojcius, Brigitte Austran, Francois A. Lemonnier, Yu-Chun Lone
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Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally-infected mice, Toni Darville, Lynn Welter-Stahl, Christiane Cruz, Ali Abdul-Sater, Charles W. Andrews Jr., David M. Ojcius
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The role of P2 receptors in controlling infections by intracellular pathogens, Robson Coutinho-Silva, Christiane Monteiro da Cruz, Pedro M. Persechini, David M. Ojcius
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ATP activates a Reactive Oxygen Species-dependent oxidative stress response and secretion of pro-inflammatory cytokines in macrophages, Christiane M. Cruz, Alessandra Rinna, Henry Jay Forman, Ana L. M. Ventura, Pedro M. Persechini, David M. Ojcius
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Host-cell survival and death during Chlamydia infection, Songmin Ying, Matthew A. Pettengill, David M. Ojcius, Georg Hacker
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Characterization of host cell death induced by Chlamydia trachomatis, Songmin Ying, Silke F. Fischer, Matthew A. Pettengill, Debye Conte, Stefan A. Paschen, David M. Ojcius, Georg Hacker
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Identification of novel HLA-DR1-restricted epitopes from the hepatitis B virus envelope protein in mice expressing HLA-DR1 and vaccinated human subjects, Anthony Pajot, Marie-Louise Michel, Maryline Mancini-Bourgine, Marie-Noelle Ungeheuer, David M. Ojcius, Qiang Deng, Francois A. Lemonnier, Yu-Chun Lone
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Stimulation of the cytosolic receptor for peptidoglycan, Nod1, by infection with Chlamydia trachomatis or Chlamydia muridarum, L. Welter-Stahl, David M. Ojcius, J. Viala, S. Girardin, W. Liu, C. Delarbre, D. Philpott, K. A. Kelley, T. Darville
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Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival, Philippe Verbeke, Lynn Welter-Stahl, S. Ying, J. Hansen, Georg Hacker, Toni Darville, David M. Ojcius
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Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X(7)-associated pore or channel formation, Christiane M. Monteiro da Cruz, Ana Lucia Marques Ventura, Julieta Schachter, Helio Miranda Costa-Junior, Hercules Antonio da Silva Souza, Fernanda Ramos Gomes, Robson Coutinho-Silva, David M. Ojcius, Pedro M. Persechini
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Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells, Özlem Yilmaz, Philippe Verbeke, Richard J. Lamont, David M. Ojcius
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Chlamydia trachomatis induces expression of IFN-g-inducible protein 10 and IFN-b independent of TLR2 and TLR4, but largely dependent on MyD88, Uma M. Nagarajan, David M. Ojcius, Lynn Stahl, Roger G. Rank, Toni Darville
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A role for mitogen-activated protein kinase (Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death, Rodolphe Auger, Iris Motta, Karim Benihoud, David M. Ojcius, Jean M. Kanellopoulos
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Can chlamydia be stopped?, David M. Ojcius, Toni Darville, Patrik M. Bavoil
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Association between coinfection of Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Treponema denticola and periodontal tissue destruction in chronic periodontitis, L. L. Chen, Y. M. Wu, J. Yan, W. L. Sun, Y. Z. Sun, David M. Ojcius
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P2X and P2Y purinergic receptors on human intestinal epithelial carcinoma cells: effects of extracellular nucleotides on apoptosis and cell proliferation, Robson Coutinho-Silva, Lynn Stahl, K. K. Cheung, N. E. de Campus, C. de Oliveira Souza, David M. Ojcius, G. Burnstock
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Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages, Robson Coutinho-Silva, David M. Ojcius, D. C. Górecki, Pedro M. Persechini, R. C. Bisaggio, A. N. Mendes, J. Marks, G. Burnstock, P. M. Dunn
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A mouse model of human adaptive immune functions: HLA-A2.1-HLA-DR1-transgenic H-2 class I-/class II-knockout mice, Anthony Pajot, Marie-Louise Michel, Nicolas Fazilleau, Veronique Pancre, Claude Auriault, David M. Ojcius, Francois A. Lemonnier, Yu-Chun Lone
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Cell death, BAX activation, and HMGB1 release during infection with Chlamydia, Thomas Jungas, Philippe Verbeke, Toni Darville, David M. Ojcius
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Chlamydia and apoptosis: life and death decisions of an intracellular pathogen, Gerald I. Byrne, David M. Ojcius
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Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei, Soo-Jin Choi, Romain Parent, Carole Guillaume, Christiane Deregnaucourt, Christiane Delarbre, David M. Ojcius, Jean-Jacques Montagne, Marie-Louise L. Celerier, Aude Phelipot, Mohamed Amiche, Jordi Molgo, Jean-Michel Camadro, Catherine Guette
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Chlamydia, Robert Belland, David M. Ojcius, Gerald I. Byrne
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Activation of the phosphatidylinositol 3-kinase/Akt pathway contributes to survival of primary epithelial cells infected with the periodontal pathogen Porphyromonas gingivalis, Özlem Yilmaz, Thomas Jungas, Philippe Verbeke, David M. Ojcius
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Comparison of HLA-DR1-directed T cell response induced in HLA-DR1 transgenic mice deficient for murine MHC class II and HLA-DR1 transgenic mice expressing endogenous murine MHC class II molecules, Anthony Pajot, Veronique Pancre, Nicolas Fazilleau, Marie-Louise Michel, Gerhild Angyalosi, David M. Ojcius, Claude Auriault, Francois A. Lemonnier, Yu-Chun Lone
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Protection against Chlamydia trachomatis infection in vitro and modulation of inflammatory response in vivo by membrane-associated glycosaminoglycans, Toni Darville, Saul Yedgar, M. Krimsky, C. W. Andrews Jr., Thomas Jungas, David M. Ojcius
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Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection, Toni Darville, Joshua M. O'Neill, Charles W. Andrews Jr., Uma M. Nagarajan, Lynn Stahl, David M. Ojcius
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Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface, Colette Kanellopoulos-Langevin, Stephane M. Caucheteux, Philippe Verbeke, David M. Ojcius
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Changes of sodium ion compartmentalization in biological systems due to pathological states. An NMR study, M. Lupu, David M. Ojcius, Jean-Luc Perfettini, J. Patry, J. L. Dimicoli, J. Mispelter
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Inhibition of chlamydial infectious activity due to P2X7 receptor-dependent phospholipase D activation, Robson Coutinho-Silva, Lynn Stahl, Marie-Noelle Raymond, Thomas Jungas, Geoffrey Burnstock, Toni Darville, David M. Ojcius, Philippe Verbeke
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Cell death and inflammation during infection with the obligate intracellular pathogen, Chlamydia, Jean-Luc Perfettini, Veronique Hospital, Lynn Stahl, Thomas Jungas, Philippe Verbeke, David M. Ojcius
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Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion, Patricia Boya, Karine Andreau, Delphine Poncet, Naoufal Zamzami, Jean-Luc Perfettini, Didier Metivier, David M. Ojcius, Marja Jäättelä, Guido Kroemer
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Characterization of a gene encoding two isoforms of a mitochondrial protein upregulated by cyclosporin A in activated T cells, Laurent Mascarell, Rodolphe Auger, Andres Alcover, David M. Ojcius, Thomas Jungas, Veronique Cadet-Daniel, Jean M. Kanellopoulos, Paolo Truffa-Bacchi
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Role of proapoptotic BAX in propagation of Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis) and the host inflammatory response, Jean-Luc Perfettini, David M. Ojcius, Charles W. Andrews Jr., Stanley J. Korsmeyer, Roger G. Rank, Toni Darville
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At the innate frontiers between mother and fetus: linking abortion with complement activation, Stephane M. Caucheteux, Colette Kanellopoulos-Langevin, David M. Ojcius
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Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator, Thomas Jungas, Iris Motta, Francis Duffieux, Pascale Fanen, Veronique Stoven, David M. Ojcius
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Absence of weight loss during Cryptosporidium infection in susceptible mice deficient in Fas-mediated apoptosis, Iris Motta, Mathieu Gissot, Jean M. Kanellopoulos, David M. Ojcius
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Inhibition of apoptosis by gamma interferon in cells and mice infected with Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis), Jean-Luc Perfettini, Toni Darville, Alice Dautry-Varsat, Roger G. Rank, David M. Ojcius
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MHC and MHC-related proteins as pleiotropic signal molecules, David M. Ojcius, Christiane Delarbre, Philippe Kourilsky, Gabriel Gachelin
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Modulation of apoptosis during infection with Chlamydia, Jean-Luc Perfettini, Mathieu Gissot, Philippe Souque, David M. Ojcius
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Role of Bcl-2 family members in caspase-independent apoptosis due to Chlamydia infection, Jean-Luc Perfettini, John C. Reed, Nicole Israel, Jean-Claude Martinou, Alice Dautry-Varsat, David M. Ojcius
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Characterization of a monoclonal antibody reacting with antigen-4 domain of gp900 in Cryptosporidium parvum invasive stages, Alain Bonnin, David M. Ojcius, Philippe Souque, Debra A. Barnes, Patricia S. Doyle, Jiri Gut, Richard G. Nelson, Carolyn Petersen, Jean-Francois Dubremetz
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Radical changes to chlamydial taxonomy are not necessary just yet, J. Schachter, R. S. Stephens, P. Timms, C. Kuo, Patrik M. Bavoil, S. Birkelund, J. Boman, H. Caldwell, L. A. Campbell, M. Chernesky, G. Christiansen, I. N. Clarke, C. Gaydos, J. T. Grayston, T. Hackstadt, R. Hsia, B. Kaltenboeck, M. Leinonnen, David M. Ojcius, G. McClarty, J. Orfila, R. Peeling, M. Puolakkainen, T. C. Quinn, R. G. Rank, J. Raulston, G. L. Ridgeway, P. Saikku, W. E. Stamm, D. T. Taylor-Robinson, S. P. Wang, P. B. Wyrick
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Modulation of P2Z/P2X7 receptor activity in macrophages infected with Chlamydia psittaci, Robson Coutinho-Silva, Jean-Luc Perfettini, Pedro M. Persechini, Alice Dautry-Varsat, David M. Ojcius
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Closing in on Chlamydia and its intracellular bag of tricks, Patrik M. Bavoil, Ru-ching Hsia, David M. Ojcius
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La notion de danger, Jean M. Kanellopoulos, David M. Ojcius
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Fluorescent labelling of intracellular bacteria in living host cells, Haralabia Boleti, David M. Ojcius, Alice Dautry-Varsat
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Effect of Chlamydia trachomatis infection and subsequent TNFa secretion on apoptosis in the murine genital tract, Jean-Luc Perfettini, Toni Darville, Gabriel Gachelin, Philippe Souque, Michel Huerre, Alice Dautry-Varsat, David M. Ojcius
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Caspase-dependent apoptosis during infection with Cryptosporidium parvum, David M. Ojcius, Jean-Luc Perfettini, Alain Bonnin, Fabrice Laurent
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Chlamydia infection or epithelial cells expressing dynamin and Eps15 mutants: clathrin-independent entry into cells and dynamin-dependent productive growth, Haralabia Boleti, Alexandre Benmerah, David M. Ojcius, Nadine Cerf-Bensussan, Alice Dautry-Varsat
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Enhancement of endocytosis due to aminophospholipid transport across the plasma membrane of living cells, E. Farge, David M. Ojcius, A. Subtil, Alice Dautry-Varsat
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Chlamydia trachomatis, ennemi intérieur : de la biologie moléculaire aux modèles animaux, Patrik M. Bavoil, David M. Ojcius, Alice Dautry-Varsat, A. Souriau, F. Bernard, A. Rodolakis, R.-C. Hsia
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P2Z-P2X7 receptor-mediated apoptosis of dendritic cells, Robson Coutinho-Silva, Pedro M. Persechini, R. C. Bisaggio, Jean-Luc Perfettini, A. C. T. Sa Neto, Jean M. Kanellopoulos, I. Motta, Alice Dautry-Varsat, David M. Ojcius
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Apoptosis of epithelial cells and macrophages due to infection with the obligate intracellular pathogen Chlamydia psittaci, David M. Ojcius, Philippe Souque, Jean-Luc Perfettini, Alice Dautry-Varsat
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Functional gene transfer from intracellular bacteria to mammalian host cells, Catherine Grillot-Courvalin, Sylvie Goussard, Francois Huetz, David M. Ojcius, Patrice Courvalin
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Enhancement of ATP levels and glucose metabolism during an infection by Chlamydia: NMR studies of living cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat
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Internalization of Chlamydia by dendritic cells and stimulation of Chlamydia-specific T cells, David M. Ojcius, Yolanda Bravo de Alba, Jean M. Kanellopoulos, Ray A. Hawkins, Kathy A. Kelly, Roger G. Rank, Alice Dautry-Varsat
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Pore-forming proteins, David M. Ojcius, Chau-Ching Liu, John Ding-E. Young
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Distribution of endosomal, lysosomal and MHC markers in a monocytic cell line infected with Chlamydia psittaci, David M. Ojcius, Raymond Hellio, Alice Dautry-Varsat
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Determinant selection for T-cell tolerance in HEL-transgenic mice: dissociation between immunogenicity and tolerogenicity, Laurent Gapin, Jean-Pierre Cabaniols, Ricardo Cibotti, David M. Ojcius, Philippe Kourilsky, Jean M. Kanellopoulos
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Heparin-mediated inhibition of Chlamydia psittaci adherence to HeLa cells, Cesar Gutiérrez-Martín, David M. Ojcius, Ru-Ching Hsia, Raymond Hellio, Patrik M. Bavoil, Alice Dautry-Varsat
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Cell suicide in health and disease, Richard C. Duke, David M. Ojcius, John Ding-E. Young
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High incidence of Coxiella burnetii markers in a rural population in France, Monique Thibon, Veronique Villiers, Philippe Souque, Alice Dautry-Varsat, Regis Duquesnel, David M. Ojcius
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Interleukin-10 inhibits tumor metastasis through an NK-cell dependent mechanism, Li-Mou Zheng, David M. Ojcius, F. Garaud, C. Roth, E. Maxwell, Z. Li, H. Rong, J. Chen, X. Y. Wang, J. J. Catino, I. King
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Presentation of antigens derived from microorganisms residing in host-cell vacuoles, David M. Ojcius, Gabriel Gachelin, Alice Dautry-Varsat
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Introduction: novel specific immunity functioning alongside classical specific immunity, G. Gachelin, I. Apostolou, David M. Ojcius
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Immunology and the confocal microscope, David M. Ojcius, F. Niedergang, A. Subtil, Raymond Hellio, Alice Dautry-Varsat
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pH and calcium dependence of hemolysis due to Rickettsia prowazekii: comparison with phospholipase activity, David M. Ojcius, M. Thibon, C. Mounier, Alice Dautry-Varsat
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Les mille et une ruses des microbes intracellulaires, David M. Ojcius, Alice Dautry-Varsat
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Role of the CDR1 of the TCR β chain in the binding to a MHC-peptide complex, Yu-Chun Lone, Maria Bellio, Ada Prochnicka-Chalufour, David M. Ojcius, Nicolas Boissel, Tom H. M. Ottenhoff, Richard D. Klausner, Jean-Pierre Abastado, Philippe Kourilsky
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Ly-49-independent inhibition of NK cell-mediated cytotoxicity by a soluble MHC class I molecule, Claude Roth, Philippe Kourilsky, David M. Ojcius
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Is antigen processing guided by major histocompatibility complex molecules?, David M. Ojcius, L. Gapin, Jean M. Kanellopoulos, Philippe Kourilsky
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Picosecond fluorescence spectroscopy of a single-chain class I major histocompatibility complex-encoded protein in its peptide loaded and unloaded states, Kerstin Dittes, D. Gakamsky, Elisha Haas, David M. Ojcius, Philippe Kourilsky, Israel Pecht, Gilad Haran
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Role for MHC class I molecules in selecting and protecting high affinity peptides in the presence of proteases, David M. Ojcius, P. Langlade-Demoyen, Gabriel Gachelin, Philippe Kourilsky
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Separate metabolic pathways leading to DNA fragmentation and apoptotic nuclear chromatin condensation, D. Sun, Shibo Jiang, Li-Mou Zheng, David M. Ojcius, John Ding-E. Young
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Cytolysis mediated by ionophores and pore-forming agents: role of intracellular calcium in apoptosis, Richard C. Duke, R. Z. Witter, P. B. Nash, John Ding-E. Young, David M. Ojcius
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Major histocompatibility complex class I molecules and resistance to infection by intracellular pathogens, David M. Ojcius, Christiane Delarbre, Philippe Kourilsky, Gabriel Gachelin
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Major contribution of the Vb chain to the antigen specificity of a TCR, Yu-Chun Lone, David M. Ojcius, M. Bellio, Philippe Kourilsky, J.-P. Abastado
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Dissociation of the peptide-MHC class I complex limits the binding rate of exogenous peptide, David M. Ojcius, Jean-Pierre Abastado, Amanda Casrouge, E. Mottez, L. Cabanie, Philippe Kourilsky
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Dissociation of the peptide/MHC class I complex: pH dependence and effect of endogenous peptides on the activation energy, David M. Ojcius, L. Gapin, Philippe Kourilsky
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Distribution of perforin-containing cells in normal and pregnant mice, Li-Mou Zheng, David M. Ojcius, John Ding-E. Young
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A soluble, single-chain Kd molecule produced by yeast selects a peptide repertoire indistinguishable from that of cell-surface-associated Kd, Jean-Pierre Abastado, David M. Ojcius, Amanda Casrouge, Patrice Yeh, Ton N. M. Schumacher, Hidde L. Ploegh, Philippe Kourilsky
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Real-time measurement of antigenic peptide binding to empty and preloaded single-chain MHC class I molecules, David M. Ojcius, Francois Godeau, Jean-Pierre Abastado, Jean-Laurent Casanova, Philippe Kourilsky
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Binding of alanine-substituted peptides to the MHC class I protein Kd, David M. Ojcius, Jean-Pierre Abastado, F. Godeau, Philippe Kourilsky
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Perforin-containing cells during spontaneous abortion, Li-Mou Zheng, David M. Ojcius, John Ding-E. Young
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Purification and ligand binding of a soluble class I MHC molecule consisting of the first three domains of H-2Kd fused to b2-microglobulin expressed in the baculovirus/insect cell system, Francois Godeau, Immanuel F. Luescher, David M. Ojcius, Cecile Saucier, Estelle Mottez, Lucien Cabanie, Philippe Kourilsky
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Channel forming activity of the perforin N-terminus and an a-helical region homologous with complement C9, P. M. Persechini, David M. Ojcius, S. C. Adeodato, Paulo C. Notaroberto, C. B. Daniel, John Ding-E. Young
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Peptide binding to MHC class I proteins measured with a novel fluorescent technique, David M. Ojcius, Jean-Pierre Abastado, F. Godeau, Philippe Kourilsky
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Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes, David M. Ojcius, Arturo Zychlinsky, Li-Mou Zheng, John Ding-E. Young
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Cytoplasts from cytotoxic T lymphocytes are resistant to perforin-mediated lysis, David M. Ojcius, Shibo Jiang, Pedro M. Persechini, Patricia A. Detmers, John Ding-E. Young
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Cell death mechanisms and the immune system, Pierre Golstein, David M. Ojcius, John Ding-E. Young
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Cytolytic and ion channel forming properties of the N-terminus of lymphocyte perforin, David M. Ojcius, Pedro M. Persechini, Li-Mou Zheng, Paulo C. Notaroberto, Sandro C. Adeodato, John Ding-E. Young
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Subcellular localization of perforin and serine esterase in lymphokine-activated killer (LAK) cells and cytotoxic T cells by immunogold labelling, David M. Ojcius, L. M. Zheng, E. C. Sphicas, A. Zychilinsky, John Ding-E. Young
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Plasma membrane-associated proteins with the ability to partially inhibit perforin-mediated lysis, David M. Ojcius, Sylviane Muller, Cynthia S. Hasselkus-Light, John Ding-E. Young, Shibo Jiang
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Role of granulated metrial gland cells in the immunology of pregnancy, Li-Mou Zheng, David M. Ojcius, John Ding-E. Young
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Cytolytic peptides and proteins: Is there a common structural motif?, David M. Ojcius, John Ding-E. Young
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Immunogold labelling of perforin and serine esterases in granulated metrial gland cells, Li-Mou Zheng, David M. Ojcius, Chau-Ching Liu, M. D. Kramer, M. M. Simon, E. L. Parr, John Ding-E. Young
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Expression of lymphocyte perforin in the mouse uterus during pregnancy, Li-Mou Zheng, Chau-Ching Liu, David M. Ojcius, John Ding-E. Young
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Extracellular ATP as a trigger for apoptosis or programmed cell death, Li-Mou Zheng, Arturo Zychlinsky, Chau-Ching Liu, David M. Ojcius, John Ding-E. Young
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Purification of a membrane-associated serine esterase from murine cytotoxic T lymphocytes by a single reverse phase column, Shibo Jiang, Cynthia S. Hasselkus-Light, David M. Ojcius, John Ding-E. Young
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Resistance to the pore forming protein of cytotoxic T cells: comparison of target cell membrane rigidity, David M. Ojcius, Shibo Jiang, Pedro M. Persechini, Judith Storch, John Ding-E. Young
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Isolation and characterization of the gene encoding the muscle-specific isozyme of human phosphoglycerate mutase,
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A role for pore-forming proteins in the pathogenesis by parasites?, David M. Ojcius, John Ding-E. Young
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Cell-mediated killing: effector mechanisms and mediators, David M. Ojcius, John Ding-E. Young
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Characterization of the inhibitory effect of lysolipids on perforin-mediated hemolysis, David M. Ojcius, John Ding-E. Young
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Resistance of cytolytic lymphocytes to perforin-mediated killing: Inhibition of perforin binding activity by surface membrane proteins, Shibo Jiang, David M. Ojcius, Pedro M. Persechini, John Ding-E. Young
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Cytotoxic effector mechanisms, David M. Ojcius, John Ding-E. Young
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Restriction factors of homologous complement: A new candidate?, David M. Ojcius, Shibo Jiang, John Ding-E. Young
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In situ mapping of the muscle-specific form of phosphoglycerate mutase gene to human chromosome 7p12-7p13, Judit Castella-Escola, M. G. Mattei, David M. Ojcius, E. Passage, C. Valentin, M. Cohen-Solal
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Perforin binding to cells and lipid membranes determined by a simple competition assay, Shibo Jiang, David M. Ojcius, John Ding-E. Young
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Review of "Current Topics in Microbiology and Immunology: Cytotoxic Effector Mechanisms", David M. Ojcius, John Ding-E. Young
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Relation between the anion exchange protein in kidney medullary collecting duct cells and red cell band 3, Agnes Janoshazi, David M. Ojcius, Bruce Kone, Julian L. Seifter, A. K. Solomon
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Is an intact cytoskeleton required for native red cell urea and water transport?, David M. Ojcius, M. R. Toon, A. K. Solomon
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