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The preparation of the coordination compounds of platinum (II) and arginine, histidine, lysine, and serine

Author

Dale Dunlop Nelson, University of the Pacific

Date of Award

1964

Document Type

Thesis

Degree Name

Master of Science (M.S.)

Department

Graduate Studies

First Advisor

Herschel Frye

First Committee Member

Emerson G. Cobb

Second Committee Member

Donald K. Wedegaertner

Abstract

The nature of this study involved the preparation of the coordination compounds of platinum (II) and four alpha-amino acids, namely arginine, histidine, lysine, and serine. A first analysis of the problem would seem to indicate that the preparations should be straightforward and not difficult. Bailar (3) stresses the great coordination tendency of the alpha-amino acids. Secondly, Volshtein (37) (38) (39) (40) (41) (41) and others have synthesized a number of platinum (II) complexes of the alpha-amino acids with apparently a minimum of difficulty in a majority of the preparations. FInally, a number of complexes of the amino acids under study have been prepared with other metals including cobalt, copper, chromium, and zinc.

Pages

59

Recommended Citation

Nelson, Dale Dunlop. (1964). The preparation of the coordination compounds of platinum (II) and arginine, histidine, lysine, and serine. University of the Pacific, Thesis. https://scholarlycommons.pacific.edu/uop_etds/391