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Date of Award

1971

Document Type

Thesis

Degree Name

Master of Science (M.S.)

Department

Biological Sciences

First Advisor

F. R. Hunter

First Committee Member

Lee Christianson

Second Committee Member

W. Michael Kaill

Abstract

Early qualitative erythrocyte permeability studies (Gryns, 1896; Hedin, 1897) revealed the wide range of non-electrolyte permeability rates across a cell membrane composed of lipid molecules. Theoretically, water-soluble non-electrolytes such as glycerol, ethylene glycol and erythritol would penetrate less rapidly than lipid-soluble non-electrolytes. It was thought that the rate of penetration of water-soluble non-electrolytes was inversely proportional to their molecular size and the penetration of lipid-soluble non-electrolytes was directly proportional to their lipid-solubility.

Pages

66

Included in

Life Sciences Commons

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