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Date of Award
Thesis - Pacific Access Restricted
Master of Science (M.S.)
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Alternative splicing of the zebrafish Myosin Phosphatase Targeting Subunit, MYPT1, produces a novel isoform (TV202). TV202 and the truncated TV202Δ ere shown to form an active complex with Protein Phosphatase 1 β (PP1β) via stress fiber assay. TV202 was also shown to be localized in the cytoplasm, enriched in a paranuclear manner. TV202Δ was found the be localized inside the nucleus. It was also found that TV202 was zygotically, but not maternally, expressed during early zebrafish development via RT-PCR.
Young, Kyle E.. (2016). Alternative splicing of the zebrafish myosin phosphatase targeting subunit, MYPT1, produces a novel isoform. University of the Pacific, Thesis - Pacific Access Restricted. http://scholarlycommons.pacific.edu/uop_etds/173
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