Title

Error propagation model for microscopic magnetic resonance elastography shear-wave images.

Document Type

Article

Publication Title

Magnetic Resonance Imaging

ISSN

0730-725X

Volume

25

Issue

1

DOI

10.1016/j.mri.2006.09.040

First Page

94

Last Page

100

Publication Date

1-1-2007

Abstract

Microscopic magnetic resonance elastography is a high-resolution method for visualizing shear waves and assessing the biomechanical viscoelastic properties of small biological samples. In this work, we used error propagation to develop a simple analytical model that relates the signal-to-noise ratio of MR magnitude images to the variance in shear-wave maps collected using gradient-echo and spin-echo phase-contrast pulse sequences. Our model predicts results for shear-wave images in phantoms, which match the experimentally observed phase variance within 8%. This model can be used to optimize MR pulse sequences for elastography studies, as well as other phase-difference techniques in MRI.