Sex-based Differences in the Aortic Function of UCD-T2DM Rats: A Novel Rat Model of Type 2 Diabetes Mellitus

Authors

Farjana Akther, University of the Pacific
Sonali Shaligram, University of the Pacific
Mujibullah Karimi, University of the Pacific
James L. Graham, University of the Pacific
Kimber L. Stanhope, University of the Pacific
Peter J. Havel, University of the Pacific
Roshanak Rahimian, University of the Pacific

Lead Author Affiliation

Physiology & Pharmacology

Introduction/Abstract

UC Davis type 2 diabetes mellitus (UCD-T2DM) Rat is a validated model of type 2 diabetes mellitus. UCDT2DM rats are characterized by polygenic, adult-onset obesity and spontaneous β-cell failure and, as a result, more closely models the pathophysiology of type 2 diabetes in humans than other rodent models of the disease.

Location

DUC Ballroom A&B

Format

Poster Presentation