Title

Characterization of Neurons Derived from a Human Induced Pluripotent Stem Cell Line Using Patch-Clamp Electrophysiology

Poster Number

28

Lead Author Affiliation

Physiology and Pharmacology

Introduction

Mechanical micro machining has drawn more attention these days in manufacturing industry due to its flexibility. Micro cutting tool is an essential component to conduct micro machining processes since it directly affects the outcome of the micro machining process. The performance of a micro cutting tool relies on its material property and geometric shape. Normally, its geometric shape is described by a few parameters such as cutting edge’s radius, rake angle, helix angle, diameter and others. It is important to measure these parameters and reconstruct micro tool’s 3D CAD model in order to monitor tool’s wear condition, perform quality control, and perform engineering analysis.

Purpose

The objective of this research is to develop a system, which is able to conduct 3D CAD model reconstruction for micro drilling tool through image processing approach

Method

The major approaches include 1) Development an experimental image acquisition system; 2) Perform 3D shape reconstruction by use of the Shape from Focus theory in a specified direction; 3) Conduct the free form curve/surface fitting using the Bezier or NURBS theory; 4) Stitch/convert the obtained free form curves/surfaces in different directions; 5) Convert the data array into a 3D CAD model, which is compatible to various commercial CAD software.

Results

Via image processing, a data point cloud is obtained. 3D CAD model is then formed through Matlab data processing and Solidworks macro construction or Parasolid data conversion.

Significance

As manufacturing tools becomes relatively smaller in size and labor becomes more expensive, it becomes much more important that an automated measurement system of high precision being built to boost manufacturing systems in their productivity.

Location

DeRosa University Center, Stockton campus, University of the Pacific

Format

Poster Presentation

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Apr 25th, 10:00 AM Apr 25th, 12:00 PM

Characterization of Neurons Derived from a Human Induced Pluripotent Stem Cell Line Using Patch-Clamp Electrophysiology

DeRosa University Center, Stockton campus, University of the Pacific

Mechanical micro machining has drawn more attention these days in manufacturing industry due to its flexibility. Micro cutting tool is an essential component to conduct micro machining processes since it directly affects the outcome of the micro machining process. The performance of a micro cutting tool relies on its material property and geometric shape. Normally, its geometric shape is described by a few parameters such as cutting edge’s radius, rake angle, helix angle, diameter and others. It is important to measure these parameters and reconstruct micro tool’s 3D CAD model in order to monitor tool’s wear condition, perform quality control, and perform engineering analysis.