Title

Effects of Energy Drinks on Blood Pressure in Caffeine Naïve Versus Non-Naïve Young Healthy Volunteers

Poster Number

10

Lead Author Affiliation

Pharmacy Practice

Introduction

Energy drinks have been claimed to increase alertness and improve mental performance. Increasing energy drink consumption in recent years has raised concern about its safety. Previous studies have reported that caffeinated energy shots significantly increase systolic blood pressure as compared to decaffeinated energy shots. However, the differential effects of blood pressure in caffeine naïve compared to non-naïve individuals has not been fully investigated.

Purpose

To evaluate the effects of caffeinated and decaffeinated 5-hour Energy shots on blood pressure in caffeine naïve versus nonnaïve young healthy volunteers.

Method

Individual patient data from two randomized, double-blinded, controlled crossover studies were combined and analyzed Subjects were. Subjects in both studies received a regular caffeinated and a decaffeinated 5-hour Energy shot separated by a washout period of six days. categorized caffeine naïve (consuming <1 cup of caffeinated beverage a day) or non-naïve (consuming ≥1 cup of caffeinated beverage a day). Blood pressure was recorded at baseline, 1 hour and 3 hours after consumption of the energy shot. Data were analyzed using student’s t-test.

Results

A total of 30 healthy volunteers (40% males) were enrolled, with 20 caffeine naïve subjects and 10 caffeine non-naïve subjects. The mean age was 23.2 ± 2.39 years and mean weight was 143.07 ± 30.23 pounds. A significant increase of 7.18 ± 6.58 mmHg in systolic BP was seen in caffeine naïve subjects compared to 2.40 ± 5.65 mmHg increase in non-naïve subjects (p=0.05). Mean diastolic blood pressure changes were similar after consumption of the caffeinated energy shot. With the decaffeinated energy shot, mean systolic and diastolic blood pressures were similar between the two groups.

Significance

Caffeine naïve individuals experienced an approximately three-fold greater increase in systolic blood pressure 1 hour after consumption of a caffeinated energy shot compared to non-naïve individuals. Further research is required evaluating the true cardiovascular risk of energy drinks in caffeine naïve individuals.

Location

DeRosa University Center, Stockton campus, University of the Pacific

Format

Poster Presentation

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Effects of Energy Drinks on Blood Pressure in Caffeine Naïve Versus Non-Naïve Young Healthy Volunteers

DeRosa University Center, Stockton campus, University of the Pacific

Energy drinks have been claimed to increase alertness and improve mental performance. Increasing energy drink consumption in recent years has raised concern about its safety. Previous studies have reported that caffeinated energy shots significantly increase systolic blood pressure as compared to decaffeinated energy shots. However, the differential effects of blood pressure in caffeine naïve compared to non-naïve individuals has not been fully investigated.