Additional Authors

Nathan Ching, DDS 2024

Presentation Category

Research

Introduction/Context/Diagnosis

Objectives: Conditioned Pain Modulation (CPM) is an emerging topic of discussion in the field of orofacial pain. It has been observed to reduce a source of pain by intentionally introducing a second source. The study investigates the efficacy of CPM in the reduction of nociception (felt pain) in order to find clinical applications in patients suffering from chronic orofacial pain syndromes. Methods: 20 members of Nihon University were randomly selected. They were first administered a painful stimulus to the TMJ and then were told to rate the pain on a visual analog scale. They were then exposed to an alterrnative stimulus via their hand in a cold water bath of varying temperatures. They were then administered the same original painful stimului and rated the VAS once again. Results: Data was collected from the participants in the CPM study and statistically analyzed. The average CPM was calculated and plotted on bar graphs. Standard error and p-values were calculated to determine the validity and correlation of the data. Conclusions: The CPM study provided statistically-significant results. There was a noticed reduction in nociceptive pain from patients after being exposed to CPM. Notably, more severe stimulus of CPM resulted in greater reduction in nociception. Additionally the more prolonged the original painful stimuli was, the more effective CPM was at reducing the pain. This data provides strong implications in applying CPM into a clinical setting. Acknowledgements: I would like to thank the entire oral medicine team at the Nihon University for their hospitality and collaboration. I would also like to thank Dr. Andrew Young for the once in a lifetime opportunity to conduct dental research overseas.

Comments/Acknowledgements

Presentation Category: Research

Location

Arthur A Dugoni School of Dentistry, 155 5th St, San Francisco, CA 94103, USA

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Presentation

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May 8th, 2:15 PM May 8th, 5:00 PM

Reduction of Temporomandibular Joint Nociception Through Conditioned Pain Modulation

Arthur A Dugoni School of Dentistry, 155 5th St, San Francisco, CA 94103, USA

Objectives: Conditioned Pain Modulation (CPM) is an emerging topic of discussion in the field of orofacial pain. It has been observed to reduce a source of pain by intentionally introducing a second source. The study investigates the efficacy of CPM in the reduction of nociception (felt pain) in order to find clinical applications in patients suffering from chronic orofacial pain syndromes. Methods: 20 members of Nihon University were randomly selected. They were first administered a painful stimulus to the TMJ and then were told to rate the pain on a visual analog scale. They were then exposed to an alterrnative stimulus via their hand in a cold water bath of varying temperatures. They were then administered the same original painful stimului and rated the VAS once again. Results: Data was collected from the participants in the CPM study and statistically analyzed. The average CPM was calculated and plotted on bar graphs. Standard error and p-values were calculated to determine the validity and correlation of the data. Conclusions: The CPM study provided statistically-significant results. There was a noticed reduction in nociceptive pain from patients after being exposed to CPM. Notably, more severe stimulus of CPM resulted in greater reduction in nociception. Additionally the more prolonged the original painful stimuli was, the more effective CPM was at reducing the pain. This data provides strong implications in applying CPM into a clinical setting. Acknowledgements: I would like to thank the entire oral medicine team at the Nihon University for their hospitality and collaboration. I would also like to thank Dr. Andrew Young for the once in a lifetime opportunity to conduct dental research overseas.

 
 

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