A path forward for the chlamydial virulence factor CPAF

ORCiD

David M. Ojcius: 0000-0003-1461-4495

Department

Biomedical Sciences

Document Type

Article

Publication Title

Microbes and Infection

ISSN

1286-4579

Volume

15

Issue

14--15

DOI

10.1016/j.micinf.2013.09.008

First Page

1026

Last Page

1032

Publication Date

12-1-2013

Abstract

CPAF is a conserved and secreted protease from obligate intracellular bacteria of the order Chlamydiales. Recently, it was demonstrated that most of its host targets are an artifact of inaccurate methods. This review aims to summarize key features of CPAF and propose new approaches for evaluating its role in chlamydial pathogenesis.

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