Title

In situ mapping of the muscle-specific form of phosphoglycerate mutase gene to human chromosome 7p12-7p13

ORCiD

David M. Ojcius: 0000-0003-1461-4495

Document Type

Article

Publication Title

Human Genetics

ISSN

0340-6717

Volume

84

Issue

2

DOI

10.1007/BF00208945

First Page

210

Last Page

212

Publication Date

1-1-1990

Abstract

A 2.3-kb-long probe derived from the 5′ flanking region, the first exon and part of the first intron of the human muscle-specific phosphoglycerate mutase gene (PGAM-M) (EC 5.4.2.1) was used to map the gene by “in situ” chromosomal hybridization. The structural gene for PGAM-M was assigned to chromosome 7p12-7p13; a single hybridization peak indicated that there is a single gene for this isozyme of PGAM, and confirmed results obtained by Southern blot hybridization.