A selection of published journal articles from faculty members of the Arthur A. Dugoni School of Dentistry at University of the Pacific.

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Submissions from 2017

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Isolation, Culture and Characterization of Hirsutella sinensis Mycelium from Caterpillar Fungus Fruiting Body, Yun-Fei Komi, Jian-Ching Liau, Chien-Sheng Lee, Chen-Yaw Chiu, Jan Martel, Chuan-Sheng Lin, Shan-Fu Tseng, David M. Ojcius, Chia-Chen Lu, Hsin-Chih Lai, and John Ding-E. Young

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Anti-obesogenic and antidiabetic effects of plants and mushrooms, Jan Martel, David M. Ojcius, Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Shun-Fu Tseng, Hsin-Chih Lai, John Ding-E. Young, and Yun-Fei Ko

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Pinicolol B from Antrodia cinnamomea induces apoptosis of nasopharyngeal carcinoma cells, Tsung-Ru Wu, Tsung-Teng Huang, Jan Martel, Jian-Ching Liau, Chen-Yaw Chiu, Yann-Lii Leu, Wei-Ting Jian, I-Te Chang, Chia-Chen Lu, David M. Ojcius, Yun-Fei Ko, Hsin-Chih Lai, and John Ding-E. Young

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MicroRNAs Modulate Pathogenesis Resulting from Chlamydial Infection in Mice, Laxmi Yeruva, S. Pouncey, Michael R. Eledge, Sudeepa Bhattacharya, Chunqiao Luo, Erin W. Weatherford, David M. Ojcius, and Roger G. Rank

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Creation of an immunodeficient HLA-transgenic mouse (HUMAMICE) and functional validation of human immunity after transfer of HLA-matched human cells, Yang Zeng, Bingrun Liu, Marie-Therese Rubio, Xinyue Wang, David M. Ojcius, Ruoping Tang, Antoine Durrbach, Zhitao Ru, Yusen Zhou, and Yu-Chun Lone

Submissions from 2016

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Purinergic signaling during Porphyromonas gingivalis infection, Cassio Luiz Coutinho Almeida-da-Silva, Ana Carolina Morandini, David M. Ojcius, Robson Coutinho-Silva, and Henning Ulrich

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Nucleoside-Diphosphate-Kinase of P. gingivalis is Secreted from Epithelial Cells In the Absence of a Leader Sequence Through a Pannexin-1 Interactome, Kalina Atanasova, Jungnam Lee, JoAnn Roberts, Kyulim Lee, David M. Ojcius, and Özlem Yilmaz

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Fusobacterium nucleatum infection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1β and the danger signals ASC and HMGB1, F. Q. Bui, L. Johnson, JoAnn Roberts, S. C. Hung, J. Lee, K. R. Atanasova, P. R. Huang, Özlem Yilmaz, and David M. Ojcius

Modulation of host immune response by Bacteroides fragilis polysaccharides: a review of recent observations, Chih-Jung Chang, Chuan-Sheng Lin, Jan Martel, David M. Ojcius, W. F. Lai, Chia-Chen Lu, Yun-Fei Ko, John Ding-E. Young, and Hsin-Chih Lai

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Pretreatment with a heat-killed probiotic modulates monocyte chemoattractant protein-1 and reduces the pathogenicity of influenza and enterovirus 71 infections, M. F. Chen, K. F. Weng, S. Y. Huang, Y. C. Liu, S. N. Tseng, David M. Ojcius, and S. R. Shih

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Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis, I-Che Chung, Chun-Nan OuYang, Sheng-Ning Yuan, Hsin-Pai P. Li, Jeng-Ting Chen, Hui-Ru Shieh, Yu-Jen Chen, David M. Ojcius, Ching-Liang Chu, Jau-Song Yu, Yu-Sun Chang, and Lih-Chyang Chen

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An iron detection system determines bacterial swarming initiation and biofilm formation, Chuan-Sheng Lin, Yu-Huan Tsai, Chih-Jung Chang, Shun-Fu Tseng, Tseng-Ru Wu, Chia-Chen Lu, Ting-Shu Wu, Jang-Jih Lu, Jim-Tong Horng, Jan Martel, David M. Ojcius, Hsin-Chih Lai, and John Ding-E. Young

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Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicity, Chia-Chen Lu, Ya-Jing Hsu, Chih-Jung Chang, Chuan-Sheng Lin, Jan Martel, David M. Ojcius, Yun-Fei Ko, Hsin-Chih Lai, and John Ding-E. Young

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Alternative functions for the multifarious inflammasome, Jan Martel, Hsin-Chih Lai, Yun-Fei Ko, John Ding-E. Young, and David M. Ojcius

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Hepatitis C virus frameshift/alternate reading frame protein suppresses interferon responses mediated by pattern recognition receptor retinoic-acid-inducible gene-I, Seung Bum Park, Scott Seronello, Wasima Mayer, and David M. Ojcius

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Danger signals, inflammasomes, and the intricate lives of chlamydiae, Matthew A. Pettengill, Ali A. Abdul-Sater, Robson Coutinho-Silva, and David M. Ojcius

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Is the inflammasome relevant for epithelial cell function?, Patricia T. Santana, Jan Martel, Hsin-Chih Lai, Jean-Luc Perfettini, Jean M. Kanellopoulos, John Ding-E. Young, Robson Coutinho-Silva, and David M. Ojcius

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Orofacial Pain Overview: Getting Rid of the Riddles, Andrew L. Young

Submissions from 2015

Stimulation and repression of cancer development by caveolae and nitric oxide, C. M. Blouin and David M. Ojcius

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Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota, Chih-Jung Chang, Chuan-Sheng Lin, Chia-Chen Lu, Jan Martel, Yun-Fei Ko, David M. Ojcius, Shun-Fu Tseng, Tsung-Ru Wu, Yi-Yuan Margaret Chen, John Ding-E. Young, and Hsin-Chih Lai

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Eosinophils from murine lamina propria induce differentiation of naïve T cells into regulatory T cells via TGF-β1 and retinoic acid, Hong-Hu Chen, Ai-Hua Sun, David M. Ojcius, Wei-Lin Hu, Yu-Mei Ge, Xu'ai Lin, Lan-Juan Li, Jian-Ping Pan, and Jie Yan

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Intracellular bacterial pathogens: a reemerging field of research rich with breakthroughs and opportunities, Gilbert Greub, Chantal P. Bleeker-Rovers, Jason Carlyon, Pierre-Edouard Fournier, David M. Ojcius, and Mirja Puolakkainen

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MERS – a cautionary tale, Sophia Hafner and David M. Ojcius

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Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo, Tsung-Teng Huang, Hsin-Chih Lai, Yun-Fei Ko, David M. Ojcius, Ying-Wei Lan, Jan Martel, John Ding-E. Young, and Kowit-Yu Chong

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Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase, Larry Johnson, Kalina R. Atanasova, Phuong Q. Bui, Jungnam Lee, Shu-Chen Hung, Özlem Yilmaz, and David M. Ojcius

Introduction to miniseries on DNA and cancer, J. M. Kanellopoulos and David M. Ojcius

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ChpK and MazF of the toxin-antitoxin modules are involved in the virulence of Leptospira interrogans during infection, Komi Koukoura Komi, Yu-Mei Ge, Xiao-Yang Xin, David M. Ojcius, Dexter Sun, Wei-Lin Hu, Xin Zhao, Xu'ai Lin, and Jie Yan

Mushrooms – from cuisine to clinic, Jan Martel, David M. Ojcius, Hsin-Chih Lai, and John Ding-E. Young

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A dual role for P2X7 receptor during Porphyromonas gingivalis infection, E. S. Ramos-Junior, Ana Carolina Morandini, C. L. Almeida-da-Silva, E. J. Franco, J. Potempa, K. A. Nguyen, A. C. Oliveira, D. S. Zamboni, David M. Ojcius, J. Scharfstein, and Robson Coutinho-Silva

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Aggregatibacter actinomycetemcomitans cytolethal distending toxin activates the NLRP3 inflammasome in human macrophages leading to the release of pro-inflammatory cytokines, Bruce J. Shenker, David M. Ojcius, Lisa P. Walker, Ali Zekavat, Monika Damek Scuron, and Kathleen Boesze-Battaglia

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Nanoparticle conversion to biofilms: in vitro demonstration using serum-derived mineralo-organic nanoparticles, Tsui-Yin Wong, Hsin-Hsin Peng, Cheng-Yeu Wu, Jan Martel, David M. Ojcius, Fu-Yung Hsu, and John Ding-E. Young

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Detection and characterization of mineralo-organic nanoparticles in human kidneys, Tsui-Yin Wong, Cheng-Yeu Wu, Jan Martel, Cheng-Wei Lin, Fu-Yung Hsu, David M. Ojcius, Paul Y. Lin, and John Ding-E. Young

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A new frontier: oral microbes without borders, Özlem Yilmaz and David M. Ojcius

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Internal Derangements of the Temporomandibular Joint: A review of the anatomy, diagnosis, and management, Andrew L. Young

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Activation of the NLRP3 inflammasome by vault nanoparticles expressing a chlamydial epitope, Ye Zhu, Janina Jiang, Najwane Said-Sadier, Gale Boxx, Cheryl Champion, Ashley Tetlow, Valerie A. Kickhoefer, Leonard H. Rome, David M. Ojcius, and Kathleen A. Kelly

Submissions from 2014

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TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans, Mufadhal Al-Kuhlani, James Rothchild, Sukumar Pal, Luis M. de la Maza, Sander Ouberg, Servaas A. Morré, Deborah Dean, and David M. Ojcius

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Is the hoopla over CPAF justified?, Georg Hacker, Dagmar Heuer, and David M. Ojcius

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cis-Resveratrol produces anti-inflammatory effects by inhibiting canonical and non-canonical inflammasomes in macrophages, Tsung-Teng Huang, Hsin-Chih Lai, Young-Bin Chen, Lih-Geeng Chen, Yi-Hui Wu, Yun-Fei Kourilsky, Chia-Chen Lu, Chih-Jung Chang, Cheng-Yeu Wu, Jan Martel, David M. Ojcius, Kowit-Yu Chong, and John Ding-E. Young

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The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome, Tsung-Teng Huang, Sian-Pu Wu, Kowit-Yu Chong, David M. Ojcius, Yun-Fei Ko, Yi-Hui Wu, Cheng-Yeu Wu, Chia-Chen Lu, Jan Martel, John Ding-E. Young, and Hsin-Chih Lai

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Valley fever: danger lurking in a dust cloud, Larry Johnson, Erin M. Gaab, Javier Sanchez, Phuong Q. Bui, Clarissa J. Nobile, Katrina K. Hoyer, Michael W. Peterson, and David M. Ojcius

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Identification of collagenase as a critical virulence factor for invasiveness and transmission of pathogenic Leptospira species, Kokouvi Kassegne, Weilin Hu, David M. Ojcius, Dexter Sun, Yu-Mei Ge, Jinfang Zhao, X. Frank Yang, Lanjuan Li, and Jie Yan

Impact of the gut microbiota, prebiotics, and probiotics on human health and disease, C. S. Lin, Chih-Jung Chang, Chau-Ching Liu, Jan Martel, David M. Ojcius, Yun-Fei Kourilsky, John Ding-E. Young, and Hsin-Chih Lai

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The pathological effects of CCR2+ inflammatory monocytes are amplified by an IFNAR1-triggered chemokine feedback loop in highly pathogenic influenza infection, Sue-Jane Lin, Ming Lo, Rei-Lin Kuo, Shin-Ru Shih, David M. Ojcius, Jean Lu, Chien-Kuo Lee, Hui-Chen Chen, Meei Yun Lin, Chuen-Miin Leu, Chia-Ni Lin, and Ching-Hwa Tsai

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Methyl-accepting chemotaxis proteins 3 and 4 are responsible for Campylobacter jejuni chemotaxis and jejuna colonization in mice in response to sodium deoxycholate, Zhifeng Li, Hongqiang Lou, David M. Ojcius, Aihua Sun, Dexter Sun, Jinfang Zhao, Xu'ai Lin, and Jie Yan

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NK cells kill mycobacteria directly by releasing perforin and granulysin, Chia-Chen Lu, Ting-Shu Wu, Ya-Jing Hsu, Chih-Jung Chang, Chuan-Sheng Lin, Ju-Hsin Chia, Tsu-Lan Wu, Tsung-Teng Huang, Jan Martel, David M. Ojcius, John Ding-E. Young, and Hsin-Chih Lai

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Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion, A. C. Morandini, E. S. Ramos-Junior, J. Potempo, K. A. Nguyen, A. C. Oliveira, M. Bellio, David M. Ojcius, J. Scharfstein, and Robson Coutinho-Silva

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Another year of microbial pathogens and the host immune response, David M. Ojcius

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The twin block: a simple technique to block both the masseteric and the anterior deep temporal nerves with one anesthetic injection, Samuel Y. P. Quek, Andrew L. Young, and Gayathri Subramanian

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Chlamydia trachomatis infection increases the expression of inflammatory tumorigenic cytokines and chemokines as well as components of the Toll-like receptor and NF-κB pathways in human prostate epithelial cells, H. Sellami, Najwene Saïd-Sadier, A. Znazen, R. Gdoura, David M. Ojcius, and A. Hammami

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The microtubule-associated protein, EB1, links AIM2 inflammasomes with autophagy-dependent secretion, Li-Jie Wang, Hsin-Yi Huang, Meng-Pin Huang, Willisa Liou, Ya-Ting Chang, Chih-Ching Wu, David M. Ojcius, and Yu-Sun Chang

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A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells, Kuo-Feng Weng, Chuan-Tien Hung, Po-Ting Hsieh, Mei-Ling L. Li, Guang-Wu Chen, Yu-An Kung, Peng-Nien Huang, Rei-Lin Kuo, Li-Lien Chen, Jing-Yi Lin, Robert Yung-Liang Wang, Shu-Jen Chen, Petrus Tang, Jim-Tong Horng, Hsing-I Huang, Jen-Ren Wang, David M. Ojcius, Gary Brewer, and Shin-Ru Shih

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Identification of CD24 as a cancer stem cell marker in human nasopharyngeal carcinoma, Chun-Hung Yang, Hui-Ling Wang, Yi-Sheng Lin, K. P. Shravan Kumar, Hung-Chi Lin, Chih-Jung Chang, Chia-Chen Lu, Tsung-Teng Huang, Jan Martel, David M. Ojcius, Yu-Sun Chang, John Ding-E. Young, and Hsin-Chih Lai

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Characterization of severe fever with thrombocytopenia syndrome in rural regions of Zhejiang, China, Lei Zhang, Ling Ye, David M. Ojcius, Xiuyu Lou, Chengwei Wang, Cen Feng, Yi Sun, Zhongfa Wang, Shibo Li, and Yanjun Zhang

Submissions from 2013

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Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin, Chih-Jung Chang, Yi-Yuan M. Chen, Chia-Chen Lu, Chuan-Sheng Lin, Jan Martel, Sheng-Hui Tsai, Yun-Fei Ko, Tsung-Teng Huang, David M. Ojcius, John Ding-E. Young, and Hsin-Chih Lai

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Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7 receptor / NADPH-oxidase signaling and contributes to persistence, C. H. Choi, R. Spooner, J. DeGuzman, T. Koutouzis, David M. Ojcius, and Özlem Yilmaz

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A path forward for the chlamydial virulence factor CPAF, Turner A. Conrad, Zhangsheng Yang, David M. Ojcius, and Guangming Zhong

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CD1d-restricted NKT cells modulate placental and uterine leukocyte populations during chlamydial infection in mice, Mohamed Habbeddine, Philippe Verbeke, Christiane Delarbre, Rene Moutier, Stephane Prieto, David M. Ojcius, and Colette Kanellopoulos-Langevin

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Hirsutella sinensis mycelium suppresses interleukin-1b and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes, Tsung-Teng Huang, Kowit-Yu Chong, David M. Ojcius, Yi-Hui Wu, Yun-Fei Ko, Cheng-Yeu Wu, Jan Martel, Chia-Chen Lu, Hsin-Chih Lai, and John Ding-E. Young

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p53 signalling controls cell cycle arrest and caspase-independent apoptosis in macrophages infected with pathogenic Leptospira species, W. Huang, Yu-Mei Ge, David M. Ojcius, Dexter Sun, H. Dong, X. F. Yang, and Jie Yan

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P2X4 assembles with P2X7 and pannexin-1 in gingival epithelial cells and modulates reactive oxygen species production and inflammasome activation, Shu-Chen Hung, Chul Hee Choi, Najwane Said-Sadier, Larry Johnson, Kalina Rosenova Atanasova, Hanen Sellami, Özlem Yilmaz, and David M. Ojcius

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Stellate ganglion block as an early intervention in sympathetically maintained headache and orofacial pain Caused by Temporal Arteritis, Noboru Noma, Hiroshi Kamo, Yuka Nakaya, Ko Dezawa, Andrew L. Young, Junad Khan, and Yoshiki Imamura

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Characterizing the intracellular distribution of metabolites in intact Chlamydia-infected cells by Raman and two-photon microscopy, Marta Szaszak, Jiun Chiun Chang, Weinan Leng, Jan Rupp, David M. Ojcius, and Anne Myers Kelley

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Transcription factor complex AP-1 mediates inflammation initiated by Chlamydia pneumoniae infection, A. Wang, M. Al-Kuhlani, S. C. Johnston, David M. Ojcius, J. Chou, and D. Dean

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Membrane vesicles nucleate mineralo-organic nanoparticles and induce carbonate apatite precipitation in human body fluids, Cheng-Yeu Wu, Jan Martel, Wei-Yun Cheng, Chao-Chih He, David M. Ojcius, and John Ding-E. Young

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Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China, Lei Zhang, Jie Yan, David M. Ojcius, Huakun Lv, Ziping Miao, Yin Chen, Yanjun Zhang, and Jvying Yan

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Identification of Leptospira interrogans phospholipase C as a novel virulence factor responsible for intracellular free calcium ion elevation during macrophage death, Jing-Fang Zhao, Hong-Hu Chen, David M. Ojcius, Xin Zhao, Dexter Sun, Yu-Mei Ge, Lin-Li Zheng, Xu'ai Lin, Lan-Juan Li, and Jie Yan

Submissions from 2012

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Activation of an NLRP3 inflammasome restricts Mycobacterium kansasii infection, Chang-Chieh Chen, Sheng-Hui Tsai, Chia-Chen Lu, Shiau-Ting Hu, Ting-Shu Wu, Tsung-Teng Huang, Najwane Saïd-Sadier, David M. Ojcius, and Hsin-Chih Lai

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Tumour inflammasome-derived IL-1b recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma, Lih-Chyang Chen, Li-Jie Wang, Nang-Ming Tsang, David M. Ojcius, Chia-Chen Chen, Chun-Nan OuYang, Chuen Hsueh, Ying Liang, Kai-Ping Chang, Chiu-Chin Chen, and Yu-Sun Chang

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Role of extracellular nucleotides in the immune response against intracellular bacteria and protozoan parasites, Robson Coutinho-Silva and David M. Ojcius

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The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages, Tsung-Teng Huang, David M. Ojcius, John Ding-E. Young, Yi-Hui Wu, Yun-Fei Ko, Tsui-Yin Wong, Cheng-Yeu Wu, Chia-Chen Lu, and Hsin-Chih Lai

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Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol, Hsin-Chih Lai, Chih-Jung Chang, Chun-Hung Yang, Ya-Jing Hsu, Chang-Chieh Chen, Chuan-Sheng Lin, Yu-Huan Tsai, Tsung-Teng Huang, David M. Ojcius, Ying-Huang Tsai, and Chia-Chen Lu

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Physicochemical and biological properties of biomimetic mineralo-protein nanoparticles formed spontaneously in biological fluids, Hsin-Hsin Peng, Cheng-Yeu Wu, David Young, Jan Martel, Andrew Young, David M. Ojcius, Yu-Hsiu Lee, and John Ding-E. Young

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Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells, Matthew A. Pettengill, Verissa W. Lam, Ikechukwu Ollawa, Camila Marques-da-Silva, and David M. Ojcius

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Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X4 receptors, Matthew A. Pettengill, Camila Marques-da-Silva, Maria Luisa Avila, Verissa W. Lam, Ikechukwu Ollawa, Ali Abdul-Sater, Robson Coutinho-Silva, Georg Hacker, David M. Ojcius, and Suellen d'Arc dos Santos Oliveira

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Development of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope protein, Zhitao Ru, Wenjun Xiao, Anthony Pajot, Zhihua Kou, Shihui Sun, Benard Maillere, Guangyu Zhao, David M. Ojcius, Yu-Chun Lone, and Yusen Zhou

Alarmins, inflammasomes and immunity, Najwane Saïd-Sadier and David M. Ojcius

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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Jargalsaikhan Dagvadori, Norika Chiba, Shuang Chen, V. Krishnan Ramanujan, Andrea J. Wolf, Laurent Vergnes, David M. Ojcius, Altan Rentsendorj, Mario Vargas, Candace Guerrero, Yinsheng Wang, Katherine A. Fitzgerald, David M. Underhill, Terrence Town, and Moshe Arditi

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Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways, Huan Wang, Yifei Hu, David M. Ojcius, X. Frank Yang, Chenglin Zhang, Shibiao Ding, Xu'ai Lin, and Jie Yan

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Interactome-wide analysis identifies end-binding protein 1 as a crucial component for the speck-like particle formation of activated absence in melanoma 2 (AIM2) inflammasomes, Li-Jie Wang, Chia-Wei Hsu, Chiu-Chin Chen, Ying Liang, Lih-Chyang Chen, David M. Ojcius, Ngan-Ming Tsang, Chuen Hsueh, Chih-Ching Wu, and Yu-Sun Chang

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Rapid and sensitive identification of RNA from the emerging pathogen, coxsackievirus A6, Lei Zhang, Xinying Wang, Yanjun Zhang, Liming Gong, Haiyan Mao, Cen Feng, David M. Ojcius, and Jie Yan

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The mammalian cell entry (Mce) protein of pathogenic Leptospira species is responsible for RGD motif-dependent infection of cells and animals, Lei Zhang, Chenglin Zhang, David M. Ojcius, Dexter Sun, Jinfang Zhao, Xu'ai Lin, Liwei Li, Lanjuan Li, and Jie Yan

Submissions from 2011

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Altered pathogenicity for seasonal influenza virus by single reassortment of the RNP genes derived from the 2009 pandemic influenza virus, Erh-Fang Hsieh, Sue-Jane Lin, Chee-Keng Mok, Guang-Wu Chen, Chih-Heng Huang, Yeau-Ching Wang, Tzu-Chun Chen, Chi-Jene Chen, David M. Ojcius, and Shin-Ru Shih

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Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin, Tsung-Teng Huang, Fu-Guo Liu, Chia-Fong Wei, Chia-Chen Lu, Chang-Chieh Chen, Hung-Chi Lin, David M. Ojcius, and Hsin-Chih Lai

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Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages, Camila Marques-da-Silva, Geoffrey Burnstock, David M. Ojcius, and Robson Coutinho-Silva

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Infection with Leishmania amazonensis upregulates purinergic receptor expressionand induces host-cell susceptibility to UTP-mediated apoptosis, Camila Marques-da-Silva, M. M. Chaves, S. P. Chaves, V. R. Figliuolo, J. R. Meyer-Fernandes, S. Corte-Real, C. Lameu, H. Ulrich, David M. Ojcius, B. Rossi-Bergmann, and Robson Coutinho-Silva

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Serum-derived nanoparticles: de novo generation and growth in vitro, and internalization by mammalian cells in culture, Hsin-Hsin Peng, Jan Martel, Yu-Hsiu Lee, David M. Ojcius, and John Ding-E. Young

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Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection, Claire Séror, Marie-Therese Melki, Frederic Subra, Syed Qasim Raza, Marlene Bras, Hela Saïdi, Roberta Nardacci, Laurent Voisin, Audrey Paoletti, Frederic Law, Isabelle Martins, Alessandra Amendola, Ali A. Abdul-Sater, Fabiola Ciccosanti, Olivier Delelis, Florence Niedergang, Sylvain Thierry, Najwane Said-Sadier, Christophe Lamaze, Didier Métivier, Jerome Estaquier, Gian Maria Fimia, Laura Falasca, Rita Casetti, Nazanine Modjtahedi, Jean M. Kanellopoulos, Jean-Francois Mouscadet, David M. Ojcius, Mauro Piacentini, Marie-Lise Gougeon, Guido Kroemer, and Jean-Luc Perfetini

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Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection, Kenichi Shimada, Timothy R. Crother, Justin Karlin, Shuang Chen, Norika Chiba, V. Krishnan Ramanujan, Laurent Vergnes, David M. Ojcius, and Moshe Arditi

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Hypervirulent Chlamydia trachomatis clinical strain is a recombinant between lymphogranuloma venereum (L(2)) and D lineages, Naraporn Somboonna, Raymond Wan, David M. Ojcius, Matthew A. Pettengill, Sandeep J. Joseph, Alexander Chang, Ray Hsu, Timothy D. Read, and Deborah Dean

Submissions from 2010

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Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Verissa M. Lam, Bhavni Singh, Matthew A. Pettengill, Fraser Soares, Ivan Tattoli, Simone Lipinski, Stephen E. Girardin, Philip Rosenstiel, and David M. Ojcius

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Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome, Ali A. Abdul-Sater, Najwene Saïd-Sadier, Eduardo V. Padilla, and David M. Ojcius

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Replication or death: distinct fates of pathogenic Leptospira strain Lai within macrophages of human or mouse origin, Shijun Li, David M. Ojcius, Sumei Liao, Liwei Li, Feng Xue, Haiyan Dong, and Jie Yan

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Microbes and Infection: past, present and future, David M. Ojcius and Stefan H. E. Kaufmann

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Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase, Najwane Saïd-Sadier, Eduardo V. Padilla, Gordon Langsley, and David M. Ojcius

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Porphyromonas gingivalis infection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells, L. Yao, C. Jermanus, B. Barbetta, C. Choi, Philippe Verbeke, David M. Ojcius, and Özlem Yilmaz

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ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis, Özlem Yilmaz, Ali A. Abdul-Sater, L. Yao, T. Koutouzis, Matthew A. Pettengill, and David M. Ojcius

Submissions from 2009

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Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis, Ali A. Abdul-Sater, Evonne Koo, Georg Häcker, and David M. Ojcius

Inflammasomes bridge signalling between pathogen identification and the immune response, Ali A. Abdul-Sater, Najwene Saïd-Sadier, David M. Ojcius, O. Yilmaz, and Kathy A. Kelly

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The oral microbiota: living with a permanent guest, Maria Avila, David M. Ojcius, and Ozlem Yilmaz

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The P2X7 receptor and intracellular pathogens: a continuing struggle, Robson Coutinho-Silva, Gladys Corrêa, Ali A. Abdul-Sater, and David M. Ojcius