Variable diastereoselectivity in acylation of 2-substituted cyclohexanols
241st American Chemical Society (ACS) National Meeting & Exposition
American Chemical Society (ACS)
March 27-31, 2011
Date of Presentation
The ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition of tertiary amines was found for certain combinations of reactants and conditions.
Samoshin, A. V.,
Franz, A. H.
Variable diastereoselectivity in acylation of 2-substituted cyclohexanols.
Paper presented at 241st American Chemical Society (ACS) National Meeting & Exposition in Anaheim, CA.
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