Thio-β-D-glucosides: Synthesis and evaluation as glycosidase inhibitors and activators
248th American Chemical Society (ACS) National Meeting
American Chemical Society (ACS)
San Francisco, CA
August 10-14, 2014
Date of Presentation
Novel structurally simple 1-thio-β-D-glucopyranosides were synthesized and tested as potential inhibitors towards several fungal glycosidases from Aspergillus oryzae and Penicillium canescens. Significant selective inhibition was observed for α- and β-glucosidases, while the same compounds produced a weak to moderate activation of α- and β-galactosidases.
Samoshina, N. M.,
Samoshin, A. V.,
Dotsenko, I. A.,
Franz, A. H.,
Samoshin, V. V.
Thio-β-D-glucosides: Synthesis and evaluation as glycosidase inhibitors and activators.
Paper presented at 248th American Chemical Society (ACS) National Meeting in San Francisco, CA.
This document is currently not available here.